Browsing Sahlgrenska Academy / Sahlgrenska akademin by Subject "p53"
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Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study
(2019-03-14)Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and ... -
Pathophysiological impact of targeting the ROS-p53 axis
(2014-10-21)The goal of this PhD thesis was to define the importance of the interplay between reactive oxygen species (ROS) and their activation of the tumor suppressor p53 in development and disease. We addressed this question using ... -
Understanding the role of long non-coding RNAs in neuroblastoma development and progression
(2019-11-11)Neuroblastoma (NB), a common cancer of childhood, contributes to 15% of all pediatric cancer deaths. The improper neuronal differentiation of neural crest cells to mature neurons in the sympathetic nervous system leads to ...