Browsing Sahlgrenska Academy / Sahlgrenska akademin by Title
Now showing items 661-680 of 2867
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Directing stem cells and progenitors towards neuronal differentiation - implications for experimental therapies for Parkinson's disease
(2008-04-09)The insight that stem- and progenitor-cells contribute to replacement of nerve cells in the adult central nervous system is the basis of modern therapies for structural brain repair. Their goal is to protect, support and ... -
Discogenic pain - A diagnostic challenge
(2014-01-31)Low back pain (LBP) is a common health complaint with a lifetime prevalence up to 80%. Patients with discogenic pain constitute a minority of all with LBP but represent an important group with substantial personal consequences ... -
Discovering the capabilities of ageing persons who are born abroad: crossing norms, moving health promotion forward
(2015-01-30)To improve the possibilities for the whole population to take control over their health is an important goal for health promotion and public health. Yet, with improved possibilities for international migration and extended ... -
Disease-related malnutrition: Energy balance, body composition and functional capacity in patients on oral nutritional support after major upper gastrointestinal surgery.
(2010-05-28)Background: Patients with cancer of the upper gastrointestinal tract are susceptible to malnutrition. Surgery is the only curative treatment although the procedure may negatively impact nutritional status. The aim of this ... -
Diseases in the hip - Exploring risk for fracture and osteoarhritis
(2019-09-18)Objective: Hip fracture is the most serious condition linked to low bone mass or osteoporosis, and Sweden has one of the highest incidences in the world. The proportion of elderly is increasing in the Swedish population ... -
Disorders of the Orofacial and Gastrointestinal Tract
(2014-11-24)Orofacial granulomatosis (OFG) is a rare granulomatous disease primarily affecting children and adolescences causing lesions in the oral and facial regions such as lip/facial swelling, angular cheilitis, tag formation, ... -
Distal femur fracture in the elderly patient
(2023-05-25)Studies on the epidemiology of distal femur fractures show a vast increase in low-energy trauma-associated fractures in older ages. Age-related changes in bones lead to loss of bone matrix and increased porosity, which ... -
Distal radioulnar joint: arthroplasty and strength assessments
(2018-01-30)The growing interest in distal radioulnar (DRUJ) disorders underlines the need for further improved evaluations of treatment outcome. Load-bearing and optimising torque are important features of the DRUJ, but they are ... -
Diving and the brain
(2022-04-25)Abstract Introduction There are reports that long-term diving is associated with cognitive impairments. This raises the question if diving itself is harmful to the brain in the absence of decompression sickness ... -
Dizziness and Benign Paroxysmal Positional Vertigo among older adults - health-related quality of life and associated factors
(2020-03-10)Dizziness is a common complaint reported by more than 30% of persons over 70 years of age and accounts for 2% of all visits in healthcare annually. Benign paroxysmal positional vertigo (BPPV) is a common and treatable cause ... -
DNA damage affecting thyroidal iodide transport: an explanation to thyroid stunning
(2008-11-24)131I is widely used clinically in the treatment of Graves´ disease and differentiated thyroid cancer. However, cellular and molecular effects of 131I irradiation in relation to absorbed dose are poorly documented. For ... -
DNA methylation profiling of CNS tumors; implications for clinical diagnostics
(2022-10-05)Diffuse gliomas and meningiomas are the most common primary tumors of the central nervous system (CNS) in adults and these tumors cause significant morbidity and mortality worldwide. Deregulation of the epigenetic mechanisms, ... -
Domestic Workload and Multiple Roles. Epidemiological findings on health and sickness absence in women
(2008-10-16)Aim: The objective of this thesis was to analyse the importance of specific exposures in women’s lives to health and sickness absence; more precisely to study the association between domestic work, multiple roles and the ... -
Dopamine and the regulation of movements - significance of nigral and striatal dopamine release in normal, hemiparkinsonian and dyskinetic rats
(2009-02-02)Introduction: The nigrostriatal dopamine (DA) containing neurones are a pivotal component in the basal ganglia, a network that regulates movement. Degeneration of these neurones causes the cardinal symptoms of Parkinson’s ... -
Dopaminergic lnterference for Treatment of Schizophrenia and Alcohol Use Disorder - an experimental study in rats
(2022-05-27)The neurotransmitter dopamine is involved in several different physiological functions as well as pathological conditions. Two conditions that have been suggested to be related to a low dopaminergic tone in the ventral ... -
Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action
(2007-11-21)Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new ... -
Drama and Learning in Nursing Education. A study in first and second cycle
(2017-11-24)Aim: The overall aim of this thesis was to explore and describe the nature of students learning through drama in nursing education, in first and second cycle. Methods: Study I was conducted as an integrative review of ... -
Drug research and development - case scenarios, development process, risks and benefits
(2011-05-09)BACKGROUND AND AIMS. Drug development has been classically associated with large pharmaceutical companies developing ‘blockbuster’ drugs aimed at large patient populations through high market penetration and multiple ... -
Dual roles for hepatic lectin receptors in the clearance of chilled platelets
(2009-10-29)Platelets for transfusion are stored at room temperature because refrigerated platelets are cleared rapidly from circulation. Room temperature storage causes major inconveniences for blood banks and medical risks for ... -
Dupuytrens sjukdom i relation till exponering för handöverförda vibrationer
(Samhällsmedicin och folkhälsa, 2022-05-30)Kunskapsöversikten syftar till att specifikt besvara frågan om risk för Dupuytrens sjukdom i relation till exponering för handöverförda vibrationer. Litteraturgenomgången följde PRISMAs systematiska metod omfattande databaserna ...