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Mechanisms for control of nucleoside triphosphate hydrolysis. Effects of DNA and RNA co-factors


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Title: Mechanisms for control of nucleoside triphosphate hydrolysis. Effects of DNA and RNA co-factors
Authors: Macao, Bertil 1969-
Issue Date: 2002
University: Göteborgs universitet/University of Gothenburg
Institution: Institute of Medical Biochemistry
Institutionen för medicinsk och fysiologisk kemi
Date of Defence: 2002-05-23
Disputation: föreläsningssal Ragnar Sandberg, Medicinaregatan 7A, Göteborg, kl 09:00
Publication type: Doctoral thesis
Keywords: ATPase
GTPase
SRP
Ffh
FtsY
SRP RNA
OBP
UL9
oriS
oriS*
HSV-1
helicase.
Abstract: In energetically unfavourable biological processes "protein machines" utilize chemical energy from the hydrolysis of high-energy phosphate bonds. Thus, the hydrolysis of a nucleoside triphosphate (NTP) to nucleoside diphosphate (NDP) with the release of free orthophosphate results in a liberation of energy. In addition, proteins that work as switches or gates in order to ensure fidelity and directionality to many synthetic and signal transduction processes also use NTP hydrolysis. This thesis de... more
ISBN: 91-628-5234-5
URI: http://hdl.handle.net/2077/15554
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

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