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|Title:||Effects of GH and liver-derived IGF-I on growth and metabolism|
|Authors:||Sjögren, Klara 1970-|
|University:||Göteborgs universitet/University of Gothenburg|
|Institution:||Department of Medicine|
Avdelningen för internmedicin
|Date of Defence:||2001-03-30|
|Disputation:||Föreläsningssal Ivan Ivarsson (A1034), Medicinaregatan 3A, kl. 13.00|
|Publication type:||Doctoral thesis|
Bone mineral content
Bone mineral density.
|Abstract:||Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. The aim of this thesis was to investigate the effects of GH and liver-derived IGF-I on growth and metabolism, especially the relative importance of liver-derived IGF-I versus IGF-I expressed locall... more|
|Appears in Collections:||Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet|