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Now showing items 11-20 of 28
Gene Polymorphisms and Related Cell Markers in Periodontitis Lesions
(2009-05-18)
Inflammatory and immune reactions to microbial plaque are the predominant features of
periodontitis. Epidemiological studies revealed that differences in periodontitis among
individuals could not be explained by ...
On the Regulation of the Serine Protease t-PA and its Inhibitor PAI-1 in the Brain
(2010-09-28)
The serine protease tissue-type plasminogen activator (t-PA) is the main fibrinolytic enzyme in the vascular system, and thus plays a critical role in the dissolution of thrombi. In recent years, researchers have focused ...
Regulation of human macrophage gene expression by oxidized low density lipoprotein. Studies on tumor necrosis factor-a and global gene expression profiles
(2001)
Atherosclerosis is a multifactorial and progressive disease that is characterized by a focal thickening of the arteries caused by accumulation of lipoproteins, extracellular matrix, and the migration and proliferation of ...
Molecular mechanisms of the kidney in health and disease
(2011-05-27)
In 2010, 307 Swedish patients received a new kidney through transplantation, and the first of April 2011, 603 patients were on the kidney transplant waiting list. In Sweden over 8000 patients are presently in active uremic ...
Polycystic ovary syndrome: ovarian pathophysiology and consequences after the menopause
(2011-11-18)
Polycystic ovary syndrome
Ovarian pathophysiology and consequences after the menopause
Johanna Schmidt
Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 2011
The ...
Molecular aspects on Herpes simplex virus type 1 DNA replication and gene expression
(2017-12-22)
Herpesviruses infect a variety of animals from molluscs to humans and they have evolved in a close relationship with their hosts. In humans, we find nine herpesviruses, representing all three subfamilies of the family ...
Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression
(2014-02-10)
Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily ...
Epigenetic regulation of gene expression in the vascular endothelium
(2016-05-12)
Epigenetic mechanisms, such as DNA methylation and histone modifications, constitute one way for a cell or an organism to respond to changes in the surrounding
environment. While histone modifications are recognized to ...
Effects of Biomechanical Stress on Gene Regulation in Vascular Cells
(2007-11-16)
The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to ...
GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function
(2009-08-24)
Abstract
Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments ...