THE IMPACT OF PERSONALITY DYSFUNCTION AND MALADAPTIVE TRAITS IN ADULT ADHD

Jacobsson, Peter
2026-05-12T12:48:45Z
2026-05-12
This doctoral project examines how dimensional models of personality pathology—particularly the DSM-5 Alternative Model for Personality Disorders (AMPD)—can enhance understanding and treatment of adult Attention-Deficit/Hyperactivity Disorder (ADHD). Moving beyond traditional categorical approaches, the AMPD integrates general personality dysfunction with maladaptive traits, providing a framework for capturing the heterogeneity of adult ADHD, its variable functional impairment, and differences in treatment response. Across studies, adult ADHD was consistently associated with elevated Disinhibition and Negative Affectivity, situating the condition within contemporary dimensional models of personality and psychopathology. At the same time, variation in general personality functioning and maladaptive trait configuration contributed to clinically meaningful differences beyond symptom severity, including functional impairment and differentiation from other psychiatric conditions. These dimensions were also associated with treatment processes and outcomes. Interpersonal traits reflecting mistrust and avoidance were linked to premature discontinuation of pharmacological treatment, while elevated personality dysfunction and maladaptive traits were associated with more limited functional improvement, despite reductions in core ADHD symptoms. Taken together, the findings suggest that dimensional models of personality pathology provide clinically relevant information beyond categorical diagnosis. Incorporating the AMPD framework, particularly the assessment of personality functioning, may support more precise formulation, improve prediction of treatment adherence and outcome, and inform individualized interventions. These results align conceptually with the ICD-11 personality disorder model and highlight the potential value of integrating pharmacological and personality-informed psychological approaches to improve real-world functioning in adults with ADHD.
2026-06-04
Torsdagen 4 juni 2026, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Institute of Neuroscience and Physiology. Department of Psychiatry and Neurochemistry
SA
peter.jacobsson.2@gu.se
klarhet@telia.com
University of Gothenburg. Sahlgrenska Academyeng
978-91-8115-777-2 (TRYCK)
978-91-8115-778-9 (PDF)
https://hdl.handle.net/2077/91001
eng
I. Jacobsson, P., Hopwood, C.J., Söderpalm, B., & Nilsson, T. (2021). Adult ADHD and emerging models of maladaptive personality: a meta-analytic review. BMC Psychiatry 21, 282. https://doi.org/10.1186/s12888-021-03284-1
II. Jacobsson, P., Hopwood, C. J., Krueger, RF., Söderpalm, B., & Nilsson, T. (2024). Conceptualizing adult ADHD with the DSM alternative model of personality disorder. Personality and Mental Health, 18(4), 369–386. https://doi.org/10.1002/pmh.1632
III. Jacobsson, P., Granqvist, T., Hopwood, C. J., Krueger, R. F., Söderpalm, B., & Nilsson, T. (2025). How Do Personality Dysfunction and Maladaptive Personality Traits Predict Time to Premature Discontinuation of Pharmacological Treatment of ADHD? Journal of Attention Disorders, 29 (5), 351-362. https://doi.org/10.1177/10870547241309524
IV. Jacobsson, P., Palage, E., Hopwood, C. J., Söderpalm, B., Krueger, R. F., Tasselius, V., & Nilsson, T. (2026). Personality Pathology and Functional Outcomes During Pharmacological Treatment of Adult ADHD. Personality and Mental Health, 20(2). https://doi.org/10.1002/pmh.70071
ADHD
DSM-5 Alternative Model for Personality Disorders (AMPD)
ICD-11 Personality Disorder model
personality dysfunction
maladaptive traits
functional impairment
pharmacological treatment
premature discontinuation
THE IMPACT OF PERSONALITY DYSFUNCTION AND MALADAPTIVE TRAITS IN ADULT ADHD
The Clinical Utility of the Alternative Model for Personality Disorder in Individualizing Treatment for Adult ADHD
texteng
Doctor of Philosophy (Medicine)
Doctoral thesiseng

Files

Original bundle

Now showing 1 - 2 of 2
Loading...
Thumbnail Image
Name:
Thesis frame
Size:
872.41 KB
Format:
Adobe Portable Document Format
Loading...
Thumbnail Image
Name:
Abstract
Size:
189.12 KB
Format:
Adobe Portable Document Format

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
4.68 KB
Format:
Item-specific license agreed upon to submission
Description: