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Synthesis of Novel Inhibitors of IdeS, a Bacterial Cysteine Protease Including Studies of Stereoselective Reductive Aminations
(2011-09-30)
Abstract
The cysteine protease IdeS is an IgG degrading enzyme secreted by the bacterium Streptococcus
pyogenes to evade the human immune system. In this thesis several inhibitors of IdeS have been
synthesized and ...