Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kemi by Subject "Conformational restriction"
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Synthesis of Novel Inhibitors of IdeS, a Bacterial Cysteine Protease Including Studies of Stereoselective Reductive Aminations
(2011-09-30)Abstract The cysteine protease IdeS is an IgG degrading enzyme secreted by the bacterium Streptococcus pyogenes to evade the human immune system. In this thesis several inhibitors of IdeS have been synthesized and ...