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Vitamin B12 and folate depletion in the elderly Diagnosis, clinical correlates and causes

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Title: Vitamin B12 and folate depletion in the elderly Diagnosis, clinical correlates and causes
Authors: Lewerin, Catharina
Issue Date: 10-Nov-2006
University: Göteborg University. Sahlgrenska Academy
Institution: Inst of Medicine. Dept of Internal Medicine
Extent: 17921 bytes
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Disputation: 2006-12-01 kl. 09.00 Arvid Carlsson Medicinareg. 3 Sahlgrenska Akademin
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: aged, methylmalonic acid, homocysteine, vitamin B12, folic acid, renal function, cognition, movement, atrophic gastritis
Abstract: Subclinical vitamin B12 and folate deficiency is common in the elderly. The clinical significance remains unresolved. There is not a universally accepted set of laboratory criteria for diagnosis, however subclinical deficiency is important to diagnose since it is easy to treat. Currently available measures of vitamin concentrations are, except in pronounced deficiency, unreliable. Plasma tHcy and serum MMA are potentially more reliable markers of intracellular vitamin status. The overall aim w... more
ISBN: 91-628-6999-X
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för medicin
Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet



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