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Cardiovascular morbidity and metabolic signature in patients with rheumatoid arthritis


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/69301

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Title: Cardiovascular morbidity and metabolic signature in patients with rheumatoid arthritis
Authors: Nadali, Mitra
E-mail: mitra.nadali@gu.se
Issue Date: 9-Sep-2021
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Biomedicine. Department of Medical Microbiology and Immunology
Parts of work: I. Erlandsson M.C, Lyngfelt L, Åberg N.D, Wasén C, Espino R.A, Töyrä Silfverswärd S, Nadali M, Jood K, Andersson K.M.E, Pullerits R, Bokarewa M.I. Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis. BMC-Biomed Central Medicine (2019) 17:141
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II. Nadali M, Pullerits R, Andersson K.M.E, Töyrä Silfverswärd S, Erlandsson M.C, Bokarewa M.I. High expression of STAT3 in subcutaneous adipose tissue associates with cardiovascular risk in women with rheumatoid arthritis. International Journal of Molecular Sciences, 2017 Nov 13; 18(11):2410
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III. Nadali M, Lyngfelt L, Töyrä Silfverswärd S, Erlandsson M.C, Andersson K.M.E, Bokarewa M.I, Pullerits R. Low soluble receptor for advanced glycation end products precedes and predicts cardiometabolic events in women with rheumatoid arthritis. Frontiers in Medicine (Lausanne). 2020; 7: 594622
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IV. Erlandsson M.C, Töyrä Silfverswärd S, Nadali M, Turkkila M, Svensson M.N.D, Jonsson I-M, Andersson K.M.E, Bokarewa M.I. IGF1R signalling contributes to IL6 production and T cell dependent inflammation in rheumatoid arthritis. Biochimica et Biophysica Acta - Molecular Basis of Disease 1863 (2017) 2158–2170
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Date of Defence: 2021-10-01
Disputation: Fredagen den 1 oktober 2021, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Cardiovascular mortality
Rheumatoid arthritis
metabolic signature
Abstract: Background and objectives: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease with excess risk for cardiovascular morbidity and mortality. The treatment of RA by anti-inflammatory drugs has dramatically been improved over the resent decades. Although, articular inflammation and disability burden has been reduced, cardiovascular disease (CVD) still accounts for more than half of all the death in RA population. This cannot entirely be explained by traditional cardiovascular risk ... more
ISBN: 978-91-8009-437-5 (PDF)
978-91-8009-436-8 (TRYCK)
URI: http://hdl.handle.net/2077/69301
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för medicin

 

 

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