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Epidemiology of viral respiratory infections with focus on in-hospital influenza transmission


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Title: Epidemiology of viral respiratory infections with focus on in-hospital influenza transmission
Authors: Sansone, Martina
E-mail: martina.sansone@vgregion.se
Issue Date: 18-May-2020
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Biomedicine. Department of Infectious Diseases
Parts of work: I. Sansone M, Andersson M, Brittain - Long R, Andersson LM, Olofsson S, Westin J, Lindh M. Rhinovirus infections in western Sweden: a four-year molecular epidemiology study comparing local and globally appearing types. Eur J Clin Microbiol Infect Dis. 2013 Jul;32(7):947-54
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II. Sansone M, Wiman Å, Karlberg ML, Brytting M, Bohlin L, Andersson LM, Westin J, Nordén R. Molecular characterization of a nosocomial outbreak of influenza B virus in an acute care hospital setting. J Hosp Infect. 2019 Jan;101(1):30-37
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III. Sansone M, Andersson M, Gustavsson L, Andersson LM, Nordén R, Westin J. Extensive hospital in-ward clustering revealed by molecular characterization of influenza A virus infection. Clin Infect Dis 2020. Feb 3 [Epub ahead of print]
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IV. Sansone M, Holmström P, Hallberg S, Nordén R, Andersson LM, Westin. Antiviral prophylaxis was the most effective preventive measure identified by system dynamic modelling of healthcare-associated influenza. In manuscript.
Date of Defence: 2020-06-12
Disputation: Fredagen den 12 juni 2020, kl 13.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: influenza
rhinovirus
infection-control
hospital outbreak
nosocomial
phylogeny
polymerase chain reaction
viral transmission
whole-genome sequencing
system dynamics
Abstract: Human Rhinoviruses (HRV) and influenza viruses are respiratory pathogens which represent a major global disease burden. Healthcare-associated infections (HCAI) are increasingly recognized as a public health concern, but limited data has been published on the characteristics and epidemiology of HCAI caused by respiratory viruses. The aim of this thesis was to investigate the molecular epidemiology of HRV and influenza virus with special focus on in-hospital influenza transmission. In paper Ⅰ, 11... more
ISBN: 978-91-7833-836-8 (PRINT)
978-91-7833-837-5 (PDF)
URI: http://hdl.handle.net/2077/63619
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin

 

 

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