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Mean systemic filling pressure - from Guyton to the ICU, and back again


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Title: Mean systemic filling pressure - from Guyton to the ICU, and back again
Authors: Werner Möller, Per
E-mail: per.moller@vgregion.se
Issue Date: 1-Feb-2019
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clinical Sciences. Department of Anesthesiology & Intensive Care Medicine
Parts of work: I. Berger D., Möller P.W., Weber A., Bloch A., Blöchlinger S., Hänggi M., Søndergaard S., Jakob S., Magder S., Takala J. (2016). Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. American Journal of Physiology. Heart and Circulatory Physiology, 311(3), H794-H806
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II. Möller P.W., Winkler B., Hurni S., Heinisch P.P., Bloch A., Søndergaard S., Jakob S., Takala J., Berger D. (2017). Right atrial pressure and venous return during cardiopulmonary bypass. American Journal of Physiology. Heart and Circulatory Physiology, 313 (2), H408-H420.
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III. Möller P.W., Hana A., Heinisch P.P., Liu S., Djafarzadeh S., Hänggi M., Bloch A. , Takala J., Jakob S., Berger D. (2018). The effects of vasoconstriction and volume expansion on veno-arterial ECMO Flow. SHOCK. E-published ahead of print. Received 3 May; accepted in final form 24 May 2018.
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IV. Möller P.W., Søndergaard S., Jakob S., Takala J., Berger D. Effect of volume status on the estimation of mean systemic filling pressure. Submitted
Date of Defence: 2019-03-01
Disputation: Fredagen den 1 mars 2019, kl. 09.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: mean systemic filling pressure
venous return
right atrial pressure
positive pressure ventilation
extracorporeal membrane oxygenation
Abstract: Introduction: Mean systemic filling pressure (MSFP) is the equilibrated vascular pressure at zero flow. Venous return (VR) driving pressure (VRdP) is the difference between MSFP and right atrial pressure (RAP). In clinical research, MSFP can be estimated: MSFPinsp_hold is the zero-flow extrapolation of RAP-cardiac output data-pairs from inspiratory hold maneuvers; MSFPa is a dynamic analogue computed from clinically available hemodynamics. However, results are controversial and fundamental conce... more
ISBN: 978-91-7833-231-1 (PRINT)
ISSN: 978-91-7833-232-8 (PDF)
URI: http://hdl.handle.net/2077/57739
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper

 

 

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