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Effects of antioxidant supplementation on cancer progression


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/55966

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Title: Effects of antioxidant supplementation on cancer progression
Authors: Le Gal Beneroso, Kristell
E-mail: kristell.le.gal.beneroso@gu.se
Issue Date: 18-May-2018
University: University of Gothenburg. Sahlgrenska Academy.
Institution: Institute of Biomedicine. Department of Medical Biochemistry and Cell Biology
Parts of work: Paper I. Antioxidants can increase melanoma metastasis in mice.
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Paper II. Mitochondria-targeted antioxidants do not influence malignant melanoma and lung cancer progression in mice. Manuscript.
Date of Defence: 2018-06-08
Disputation: Fredagen den 8 juni 2018, kl. 13.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3.
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Antioxidants
ROS
Cancer
Metastasis
Abstract: Popular wisdom holds that antioxidants protect against cancer because they neutralize reactive oxygen species (ROS) and other free radicals which can otherwise cause cancer by damaging DNA. This has been the rationale behind many clinical trials with antioxidants, which in most cases failed to show a beneficial effect and in others even increased cancer incidence. Our group believes that these inconsistencies can be explained by the idea that antioxidants have opposite effects on tumor initiatio... more
ISBN: 978-91-7833-034-8 (PDF)
978-91-7833-033-1 (PRINT)
URI: http://hdl.handle.net/2077/55966
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin

 

 

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