Doctoral Theses / Doktorsavhandlingar Institutionen för medicin: Recent submissions
Now showing items 1-20 of 653
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Endovascular shunting techniques in vascular surgery
(2025-05-13)Abstract Background: Acute tissue ischaemia can lead to significant tissue damage and, in severe cases, permanent loss of organ or limb function. Temporary arterial shunting is an established technique to mitigate ... -
Computational phenotyping of obstructive airway diseases and allergy
(2025-05-13)Allergy and obstructive airway diseases, e.g., asthma, are common and may inflict substantial hardship. They are also interlinked and heterogeneous in their clinical presentations (phenotypes). Artificial intelligence (AI) ... -
The role of the gut microbiota and frailty on bone metabolism, and the risk of injurious falls and fractures
(2025-05-13)Aging is intrinsically linked to musculoskeletal decline, culminating in increased risk of frailty, falls, fractures, and associated morbidity and mortality. This thesis investigates the association between gut microbiota ... -
Birth weight and childhood overweight - exploring parental influences and future risk of coronary heart disease
(2025-04-29)Overweight and obesity now affect individuals of all ages in all parts of the world. Obesity leads to individual suffering as well as increased risk of future disease and premature death from several causes, among which ... -
Cardiovascular and renal effects of long-term particle exposure
(2025-04-25)Background and aims Long-term particle exposure is a major risk factor for cardiovascular disease, claiming millions of lives annually. However, it remains uncertain if atherosclerosis mediates the cardiovascular effects ... -
Evaluations of diet strategies in improving risk factor control in adults with type 1 diabetes
(2025-04-16)Achieving optimal glucose control remains challenging for many individuals with type 1 diabetes (T1D), leading them to explore various dietary strategies. However, evidence from dietary trials in T1D remains limited. The ... -
Bridging the gaps in mortality data and healthcare access: A novel verbal autopsy application using subnational T2DM register in Saudi Arabia
(2025-04-14)Background: Diabetes mellitus is an increasingly critical health concern in Saudi Arabia, often with other comorbidities and mortality causes, such as cardiovascular disease (CVD). National sociodemographic changes entail ... -
Abdominal pain-related disorders of gut-brain interaction from childhood to adulthood: A birth cohort study on natural history, risk factors, and quality of life
(2025-04-03)Recurrent abdominal pain (RAP) is a common issue across the lifespan and a defining feature of abdominal pain-related disorders of gut-brain interaction (AP-DGBI), including irritable bowel syndrome (IBS). These disorders ... -
Navigating digital transformation in primary care: Implementation, intention, normalization, and institutional logics
(2025-04-02)This compilation thesis examines the implementation of video consultations in primary care, focusing on how healthcare professionals navigate the digital transformation amidst conflicting priorities. It explores the value ... -
Maternal Dietary Intake and Associated Pregnancy Outcomes in the United Arab Emirates - The Dietary Subcohort of the Mutaba’ah Study
(2025-03-21)This thesis aimed to assess dietary intake and its associations with pregnancy outcomes in the United Arab Emirates (UAE). Within the Mutaba’ah Study, 1556 pregnant women were recruited into a dietary subcohort. Data ... -
Neutrophil free fatty acid receptors
(2025-02-18)The human immune system protects against threats that range from microorganisms to damaged cells. Neutrophils, which are the most numerous cells of the innate immune system, circulate in the bloodstream in abundance. In ... -
Philadelphia-Negative Myeloproliferative Neoplasms: Diagnostic Insights, Genetic Factors and Vascular Impact on Survival
(2025-02-06)The thesis addresses Philadelphia-negative myeloproliferative neoplasms (MPNs), a group of clonal hematopoietic stem cell disorders encompassing polycythemia vera (PV), essential thrombocythemia (ET), myelofibrosis (MF) ... -
Cardiopulmonary Phenotyping during Sleep - Innovative Signal Processing for Precision Medicine in Sleep Apnea
(2024-12-18)Background: Obstructive sleep apnea (OSA) is one of the most common sleep disorders with a significant impact on public health. Various studies suggest that the contemporary methods of clinical sleep medicine are ... -
Translational studies to understand myocardial stunning in acute myocardial infarction
(2024-12-18)Myocardial stunning is a reversible contractile dysfunction that persists despite the resolution of myocardial ischemia. It is commonly associated with acute myocardial infarction. However, myocardial stunning also occurs ... -
Human B-cell development at the single-cell level
(2024-11-21)B cells play an integral part of our immune system. In adults they develop in the bone marrow in a regulated process in which the specificity of their B-cell antigen receptor (BCR), a membrane bound antibody, is established. ... -
Characterization and impact of disorders of gut-brain interaction: a national and international epidemiological project
(2024-11-19)Disorders of gut-brain interaction (DGBI) are highly prevalent conditions, characterized by chronic or recurrent gastrointestinal (GI) symptoms. DGBI significantly impacts quality of life (QoL) and healthcare utilization, ... -
DNA damage in autoimmunity
(2024-11-18)Rheumatoid arthritis (RA) is the canonical autoimmune disease whose pathogenesis is tightly linked to risk factors which cause damage of DNA and affect immune cell function. DNA damage abnormally reorganizes the genome and ... -
Tobacco control policies in Vietnam: Smoking behaviors and stakeholders' perceptions
(2024-11-18)Tobacco remains a significant public health concern in Vietnam, particularly among men, with over 15 million users. It has been 12 years since the tobacco control law was enacted; however, the smoking prevalence has decreased ... -
The social determinants of self-reported mental health among adolescents in Sweden and the Nordic countries - focusing on socioeconomic inequalities
(2024-11-14)Mental health problems have increased among children and adolescents in the Nordic countries during the last decades. Such problems may have both short- and long-term negative consequences for both the individual and society ... -
Sudden cardiac arrest in relation to exercise
(2024-11-07)Background: In predisposed individuals with a known or unknown cardiovascular disease, the risk of a sudden cardiac arrest is increased during and immediately after exercise. The most common postmortem diagnosis of ...