GUPEA >
Faculty of Science / Naturvetenskapliga fakulteten >
Department of Physics / Institutionen för fysik >
Doctoral Theses / Doktorsavhandlingar Institutionen för fysik >

Microfluidic devices for single-cell and organ-level studies


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/51261

Files in This Item:

File Description SizeFormat
gupea_2077_51261_1.pdfThesis frame36407KbAdobe PDF
View/Open
gupea_2077_51261_2.pdfAbstract sheet231KbAdobe PDF
View/Open
Title: Microfluidic devices for single-cell and organ-level studies
Authors: A. Banaeiyan, Amin
E-mail: amin.banaeiyan@physics.gu.se
am.abba@gmail.com
Issue Date: 1-Mar-2017
University: Göteborgs universitet. Naturvetenskapliga fakulteten
Institution: Department of Physics ; Institutionen för fysik
Parts of work: Inhibition of MAPK Hog1 results in increased Hsp104 aggregate forma- tion probably through elevated arsenite in ux into the cells, an approach with numerous potential applications Doryaneh Ahmadpour, Amin A. Banaeiyan, Morten Gr tli, Martin Adiels, Mattias Goks or and Caroline B. Adiels American Journal of Molecular Biology, 4, 59-71, (2014).
VIEW ARTICLE


Design and fabrication of high-throughput application-speci c micro uidic devices for studying single-cell responses to extracellular perturbations Amin A. Banaeiyan, Doryaneh Ahmadpour, Caroline B. Adiels andMattias Goks or Proceedings of SPIE, International Society for Optics and Photonics, SPIE Microtechnologies, 8765, (2013).
VIEW ARTICLE


Hydrodynamic cell trapping for high throughput single-cell applications Amin A. Banaeiyan, Doryaneh Ahmadpour, Caroline B. Adiels andMattias Goks or Micromachines, 4.4, 414-430, (2013).
VIEW ARTICLE


Design and fabrication of a scalable liver-lobule-on-a-chip microphysiolog- ical platform Amin A. Banaeiyan, Jannick Theobald, Jurgita Pauk styt_e, Stefan W ol , Caroline B Adiels and Mattias Goks or Biofabrication, 9, 015014, (2017).
VIEW ARTICLE

Date of Defence: 2017-03-23
Disputation: "Torsdagen den 23 mars 2017, kl. 9.00, PJ salen, Origovägen 6B
Degree: Doctor of Philosophy
Publication type: Doctoral thesis
Keywords: Microfuidics
single-cell analysis
organ-on-a-chip
yeast
liver
hepatocytes
liver-on-a-chip
liver lobule
Abstract: The process of developing and testing drug candidates is a slow and costly endeavor. The mainstream technologies such as bulk 2D cell culture techniques have been proven insufficient to capture the pharmacokinetics and pharmacodynamics of drug compounds in humans. Animal models, despite their central role in drug development studies, fall short to predict the human-specific mechanisms of drug clearance and toxicity. In this thesis project, I have designed and evaluated application-specific singl... more
ISBN: 978-91-629-0129-5 (printed)
978-91-629-0129-1 (PDF)
URI: http://hdl.handle.net/2077/51261
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för fysik

 

 

© Göteborgs universitet 2011