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Intermittent claudication - studies on clinical evaluation strategies and invasive treatment efficacy

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Title: Intermittent claudication - studies on clinical evaluation strategies and invasive treatment efficacy
Authors: Nordanstig, Joakim
Issue Date: 15-May-2014
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Medicine. Department of Molecular and Clinical Medicine
Parts of work: I. Nordanstig J, Gelin J, Hensäter M, Taft C, Österberg K, Jivegård L. Walking Performance and Health Related Quality of Life after Surgical or Endovascular Invasive versus Non-invasive Treatment for Intermittent Claudication – a Prospective Randomised Trial. Eur J Vasc Endovasc Surg. 2011 Aug; 42(2): 220-7.

II. Nordanstig J, Karlsson J, Pettersson M, Wann-Hansson C. Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting. Health and Quality of Life Outcomes 2012, 10:45 doi: 10.1186/1477-7525-10-45.

III. Nordanstig J, Wann-Hansson C, Karlsson J, Lundström M, Pettersson M, Morgan M. Vascular Quality of Life Questionnaire-6 facilitates health-related quality of life assessment in peripheral arterial disease. J Vasc Surg. 2014; 59: 700-7.

IV. Nordanstig J, Broeren M, Hensäter M, Perlander A, Österberg K, Jivegård L. Six-minutes walk test closely correlates to “real-life” outdoor walking capacity and quality of life in patients with intermittent claudication. J Vasc Surg. 2014 Mar 29. pii: S0741-5214(14)00332-2. doi: 10.1016/j.jvs.2014.03.003. [Epub ahead of print].

V. Nordanstig J, Taft C, Hensäter M, Perlander A, Österberg K, Jivegård L. Improved quality of life and claudication distance with a primary invasive, using TASC II principles, versus a primary non-invasive treatment strategy in claudicants – one-year results of the IRONIC trial. Submitted.
Date of Defence: 2014-06-05
Disputation: Torsdagen den 5 juni 2014, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: intermittent claudication
peripheral arterial disease
endovascular procedures
quality of life
health-related quality of life
disease-specific instruments
walking capacity
walk test
Abstract: Peripheral arterial disease is a common health problem that globally affects over 200 million individuals, and intermittent claudication (IC) is the most common symptomatic presentation. The leg symptoms in IC are provoked by walking exercise and can be alleviated by medical intervention, exercise training and invasive vascular interventions (revascularization). The quality of evidence for invasive treatment is low and the efficacy, in terms of patient-oriented endpoints (e.g. health-related qua... more
ISBN: 978-91-628-8930-2 (printed version)
978-91-637-4975-9 (e-publication)
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för medicin



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