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Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers


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Title: Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers
Authors: Kristjánsdóttir, Björg
E-mail: bjorg.kristjansdottir@vgregion.se
Issue Date: 4-Nov-2013
University: University of Gothenburg, Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Obstetrics and Gynecology
Parts of work: I. Ovarian cyst fluid is a rich proteome resource for detection of new tumor biomarkers; Kristjansdottir B, Partheen K, Fung ET, Marcickiewicz J, Yip C, Brännström M, Sundfeldt K; Clinical Proteomics, 2012 Dec 27; 9(1):1,
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II. Early inflammatory response in epithelial ovarian tumor cyst fluid; Kristjansdottir B, Partheen K, Fung ET, Yip C, Levan K, Sundfeldt K; Manuscript

III. Potential tumor biomarkers identified in ovarian cyst fluid by quantitative proteomic analysis, iTRAQ; Kristjansdottir B, Levan K, Partheen K, Carlsohn, E, Sundfeldt K; Clinical Proteomics, 2013 Apr 4; 10(1):4,
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IV. Evaluation of ovarian cancer biomarkers HE4 and CA125 in women presenting with a suspicious cystic ovarian mass; Partheen K, Kristjansdottir B, Sundfeldt K; Journal of Gynecologic Oncology, 2011 Dec 22; 4:244-252,
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V. Diagnostic performance of the biomarkers HE4 and CA125 in type I and type II epithelial ovarian cancer; Kristjansdottir B, Partheen K, Levan K, Sundfeldt K; Gynecologic Oncology 2013 Jul 25; 131:52-58, Gynecologic Oncology 2013 Jul 25.
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Date of Defence: 2013-11-15
Disputation: Fredagen den 15 november 2013, kl. 9.00, Stammen, föreläsningssal Kvinnokliniken Sahlgrenska Univeritetsjukhuset/ Sahlgrenska
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Epithelial Ovarian Cancer
Ovarian cyst fluid
Tumor biomarkers
Proteomics
Pelvic mass
Mass Spectometry
SELDI-TOF MS
iTRAQ
Abstract: Early Diagnosis of Epithelial Ovarian Cancer - Analysis of Novel Biomarkers Björg Kristjánsdóttir Department of Obstetrics & Gynecology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Sweden ABSTRACT Background: Majority of epithelial ovarian cancer (EOC) is detected in advanced stage with bad prognosis and high mortality. Reliable diagnostic markers are lacking, pre-cancerous lesions in the more aggressive tumors are not clearly defined, vague or unspeci... more
ISBN: 978-91-628-8727-8
URI: http://hdl.handle.net/2077/33099
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper

 

 

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