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Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging


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Title: Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging
Authors: Leonhardt, Henrik
E-mail: henrik.leonhardt@vgregion.se
Issue Date: 10-May-2013
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Radiology
Parts of work: Paper 1. Mannerås-Holm L, Leonhardt H et al.Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance. J Clin Endocrinol Metab. 2011 Feb;96(2):E304-11.
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Paper 2. Leonhardt H, Gull B et al. Uterine morphology and peristalsis in women with polycystic ovary syndrome. Acta Radiol. 2012 Dec 1;53(10):1195-201.
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Paper 3. Leonhardt H, Gull B et al. Ovarian volume and antral follicle count assessed by MRI and transvaginal ultrasonography; a methodological study. Submitted.

Paper 4. Leonhardt H, Gull B et al. Antral follicle count and free testosterone, but not anti-Müllerian hormone, discriminate women with polycystic ovary syndrome from controls. Submitted.
Date of Defence: 2013-05-31
Disputation: Fredagen den 31 maj 2013, kl. 9.00, Sahlgrens aula, Sahlgrenska universitetssjukhuset, huvudentrén, Blå stråket 5, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: polycystic ovary syndrome
PCOS
magnetic resonance imaging
MRI
ultrasonography
three-dimensional imaging
adrenal hyperplasia
body composition
uterine morphology
uterine peristalsis
ovarian morphology
ovarian perfusion
antral follicle count
AMH
diagnostic accuracy
Abstract: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, affecting up to 15% of women of reproductive age. The syndrome is characterized by oligo-anovulation, hyperandrogenism and polycystic ovaries. What constitutes the best definition of PCOS is still a matter of debate. Women with PCOS have a higher risk of developing abdominal obesity, insulin resistance with progression to type 2 diabetes, hypertension, and endometrial hyperplasia/cancer. The etiology of PCOS remains incompletely u... more
ISBN: 978-91-628-8677-6
URI: http://hdl.handle.net/2077/32391
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper

 

 

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