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Clinical study on osteoporosis in ankylosing spondylitis

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Title: Clinical study on osteoporosis in ankylosing spondylitis
Authors: Klingberg, Eva
Issue Date: 25-Mar-2013
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Medicine. Department of Rheumatology and Inflammation Research
Parts of work: I. Klingberg E, Lorentzon M, Mellström D, Geijer M, Göthlin J, Hilme E, Hedberg M, Carlsten H, Forsblad-d’Elia H: Osteoporosis in ankylosing spondylitis – prevalence, risk factors and methods of assessment. Arthritis Research & Therapy 2012, 14(3):R108

II. Klingberg E, Geijer M, Göthlin J, Mellström D, Lorentzon M, Hilme E, Hedberg M, Carlsten H, Forsblad-d’Elia H: Vertebral fractures in ankylosing spondylitis are associated with lower bone mineral density in both central and peripheral skeleton. The Journal of Rheumatology 2012, 39(10):1987-1995.

III. Klingberg E, Nurkkala M, Carlsten H, Forsblad-d’Elia H: Biomarkers of bone metabolism in ankylosing spondylitis in relation to osteoproliferation and osteoporosis. Submitted.

IV. Klingberg E, Lorentzon M, Göthlin J, Mellström D, Geijer M, Ohlsson C, Atkinson EJ, Khosla S, Carlsten H, Forsblad-d’Elia H: Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures and syndesmophyte formation. In manuscript.

V. Klingberg E, Carlsten H, Hilme E, Hedberg M, Forsblad-d’Elia H: Calprotectin in ankylosing spondylitis – frequently elevated in feces, but normal in serum. Scandinavian Journal of Gastroenterology 2012, Apr 47(4): 435-44

Date of Defence: 2013-03-21
Disputation: Torsdagen den 21 mars 2013, kl 9.00, Föreläsningssalen (plan 3), Avdelningen för reumatologi och inflammationsforskning, Guldhedsgatan 10 A, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: ankylosing spondylitis
bone mineral density
vertebral fractures
bone microarchitecture
Abstract: ABSTRACT Ankylosing spondylitis (AS) is a disease characterized by chronic inflammation and osteoproliferation in the spine, leading to bony fusion (ankylosis) of the sacroiliacal joints, the growth of bony spurs (syndesmophytes) between the vertebras and impairment of back-mobility. Paradoxically AS patients also have an increased risk of osteoporosis and vertebral fractures. In this cross-sectional study on 210 included AS patients (New York criteria) from West Sweden we found that osteopo... more
ISBN: 978-91-628-8618-9
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för medicin



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