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Cervical dysplasia and cervical cancer in pregnancy: diagnosis and outcome


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Title: Cervical dysplasia and cervical cancer in pregnancy: diagnosis and outcome
Authors: Kärrberg, Cecilia
E-mail: cecilia.karrberg@vgregion.se
Issue Date: 15-Nov-2012
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Obstetrics and Gynecology
Parts of work: I.Histological diagnosis and evaluation of the Swede score colposcopic system in a large cohort of pregnant women with atypical cervical cytology or cervical malignancy signs Kärrberg C, Ryd W, Strander B, Brännström M, Rådberg T Acta Ob Gyn Scand, 2012;91:952-8.
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II.Colposcopically directed cervical biopsy during pregnancy; minor surgical and obstetrical complications and high rate of persistence/regression.Kärrberg C, Brännström M, Strander B, Ladfors L, Rådberg T.Submitted.

III.Incidence and treatment of cancer of the uterine cervix in pregnancy, including all cases in the Western region of Sweden 1993-2008 Kärrberg C, Rådberg T, Holmberg E, Norström A Submitted.

IV.Type-specific human papillomavirus E6/E7 mRNA detection by real-time PCR improves identification of cervical neoplasia Andersson E, Kärrberg C, Rådberg T, Blomqvist L, Zetterqvist B-M, Ryd W, Lindh M, Horal P J Clin Microbiol, 2011;49:3794-9.
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V.Could p16 INK4a and high-risk HPV mRNA analysis of liquid-based cytology identify pregnant women at risk for cervical carcinoma? Kärrberg C, Andersson E, Ryd W, Dohse M, Brännström M, Rådberg T Submitted.
Date of Defence: 2012-12-06
Disputation: Torsdagen den 6 december 2012, kl. 9.00, Stammens föreläsningssal, Kvinnokliniken, Sahlgrenska Universitetssjukhuset, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Cervical dysplasia
cervical cancer
pregnancy
colposcopic scoring system
regression
persistence
progression
HPV DNA test
HPV mRNA E6/E7 test
p16INK4a
Abstract: ABSTRACT:Cervical cancer is one of the most common types of cancer that is diagnosed during pregnancy. The primary aim in investigation of atypical cervical cytology during pregnancy is to exclude cancer so that further treatment of the lesion can be postponed until after delivery. However, there are difficulties in colposcopic evaluation of cervix due to specific changes and cancer can be overlooked if not multiple biopsies are obtained, but these invasive interventions may increase the risk of... more
ISBN: 978-91-628-8544-1
URI: http://hdl.handle.net/2077/30262
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper

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