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Stress, Homeostasis and Robustness: Molecular and Systems Level Analysis in Yeast


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Title: Stress, Homeostasis and Robustness: Molecular and Systems Level Analysis in Yeast
Authors: Ahmadpour, Doryaneh
E-mail: doryaneh.ahmadpour@cmb.gu.se
Issue Date: 2-May-2012
University: Göteborgs universitet. Naturvetenskapliga fakulteten
Institution: Department of Cell and Molecular Biology ; Institutionen för cell- och molekylärbiologi
Parts of work: Paper I: The MAPK Hog1p Modulates Fps1p-dependent Arsenite Uptake and Tolerance in Yeast
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Paper II: The MAP kinase Slt2 modulates transport through the aquaglyceroporin Fps1

Paper III: Yeast aquaglyceroporins use the transmembrane core to restrict glycerol transport

Paper IV: Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway
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Date of Defence: 2012-05-24
Disputation: Torsdagen den 24 Maj 2012, kl. 10.00, Hörsal Ragnar Sandberg, Medicinaregatan 7
Degree: Doctor of Philosophy
Publication type: Doctoral thesis
Abstract: Abstract Cells constantly encounter stress due to alterations in the external milieu or internal parameters. However, cells are robust to such changes and maintain homeostasis. Using the yeast Saccharomyces cerevisiae as a model organism, we attempted to elucidate aspects of homeostasis and robustness at both molecular and systems levels. At the molecular level, we focused on the aquaglyceroporin Fps1 and at the systems level we investigated the High Osmolarity Glycerol (HOG) pathway. Although ... more
ISBN: ISBN 978-91-628-8461-1
URI: http://hdl.handle.net/2077/28374
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för cell- och molekylärbiologi
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

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