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The impact of the progranulin-sortilin axis on breast cancer stem cell activity and patient outcome
(2021-08-18)
Breast cancer is the most common cancer in women worldwide. Still today, despite current breast cancer therapies, many patients experience treatment resistance and relapse, which are believed to be due to failure in targeting ...
Breast cancer surgery - Aspects of patient-reported outcomes and physical activity
(2021-11-15)
The aim of this thesis was to evaluate patient-reported outcomes (PROs) following breast cancer surgery using three different studies.
Paper I examined breast-conserving surgery through an inframammary fold incision using ...
The breast cancer microenvironment and cancer cell secretion - specific effects on cancer progression and subtypes of cancer cells
(2021-01-22)
Breast cancer is the cancer form responsible for the most cancer-related deaths
among women worldwide, and novel targeted therapies are highly needed. The
tumor microenvironment consists of several components, including ...
The use of immunological biomarkers to improve individualization of postoperative radiotherapy in breast cancer
(2022-09-30)
Radiotherapy (RT) forms the cornerstone of most curative breast cancer treatment due to its well-established risk-reducing effect on local recurrences at the population level. However, there is heterogeneity regarding ...
3D Printed scaffolds as cancer microenvironment medels for drug discovery
(2022-04-05)
Cancer is one of the most common diseases in the modern world and major efforts are made globally to develop new diagnostics and treatments. It originates from a cell which, at some point, has begun to divide and grow ...
Designing, developing, and evaluating a person-centered support model for women with breast cancer treated with endocrine therapy
(2022-04-19)
Breast cancer is the most common cancer among women worldwide. Approximately 70% of all breast cancers are estrogen positive and are recommended for treatment with adjuvant endocrine therapy (ET) for five to ten years, ...