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Novel cerebrospinal fluid and blood tau biomarkers in Alzheimer's disease and other neurodegenerative diseases
(2022-03-18)
Tau is a protein predominantly expressed in neurons in the central nervous system (CNS), where it binds microtubules (MT), playing a major role regulating their dynamics and architecture. Under pathological conditions, tau ...
Cerebrospinal fluid studies of bipolar disorder
(2022-04-14)
The pathophysiology of bipolar disorder remains to be elucidated. One approach to studying brain processes is analysis of cerebrospinal fluid (CSF). This thesis comprises five studies based on the Sankt Göran Bipolar Project ...
New Risk Factors in Poststroke Epilepsy
(2022-05-04)
The overall aim of the present research was to identify new risk factors for poststroke epilepsy (PSE). Specifically, we wanted to assess the impact of having a first-degree relative with epilepsy on PSE risk (Paper I), ...