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Cognitive dysfunction studied in animal models of schizophrenia
Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ...
Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome
Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although ...
Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity
Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous ...
GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function
Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments ...