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Innate and acquired immunity to herpes simplex virus type 2 glycoprotein G in humans


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Title: Innate and acquired immunity to herpes simplex virus type 2 glycoprotein G in humans
Authors: Bellner, Lars 1973-
Issue Date: 2005
University: Göteborgs universitet/University of Gothenburg
Institution: Department of Rheumatology and Inflammation Research
Avdelningen reumatologi och inflammationsforskning
Date of Defence: 2005-01-28
Disputation: Föreläsningssalen vån 3 i Mikrobiologen, Guldhedsgatan 10 A, kl. 09.00
Publication type: Doctoral thesis
Keywords: herpes simplex virus type 2
glycoprotein G-2
T-cell proliferation
Th1 cytokines
phagocytes
NK cells
reactive oxygen species
formyl peptide receptors
Abstract: Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the human genital tract mucosa and is the most common cause of genital ulcer disease in humans. The infection exhibits a broad clinical spectrum, ranging from severe recurrent episodes of genital herpes to being completely asymptomatic. The overall objective of the present thesis was to characterize the cellular immune responses to HSV-2 glycoprotein G (gG-2) in symptomatic patients, symptom-free carriers, and un... more
ISBN: 91-628-6367-3
URI: http://hdl.handle.net/2077/16428
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

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