GUPEA >
Doctoral Theses / Doktorsavhandlingar >
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet >

Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/15791

Files in This Item:

File Description SizeFormat
gupea_2077_15791_1.txtPressmeddelande1KbText
View/Open
gupea_2077_15791_3.pdfThesis22193KbAdobe PDF
View/Open
Title: Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease
Authors: Puchades, Maja Amedjkouh 1969-
Issue Date: 2003
University: Göteborgs universitet/University of Gothenburg
Institution: Institute of Clinical Neuroscience
Institutionen för klinisk neurovetenskap
Date of Defence: 2003-03-14
Disputation: Psykiatriklinikens aula, Sahlgrenska Universitets sjukhuset/ Mölndal, kl. 13.00
Publication type: Doctoral thesis
Keywords: Alzheimer's disease
cerebrospinal fluid
proteomics
mass spectrometry
biomarkers
synaptic proteins
liquid phase IEF
Abstract: Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. Although research on AD is progressing fast, the causes and mechanisms of this disease remain to be elucidated and development of new methods is necessary to study neuron-related proteins involved in the pathophysiological mechanisms. Six low-abundance synaptic proteins in huma... more
ISBN: 91-628-5572-7
URI: http://hdl.handle.net/2077/15791
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

 

 

© Göteborgs universitet 2011