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An intact renin-angiotensin system is essential for normal renal development


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Title: An intact renin-angiotensin system is essential for normal renal development
Authors: Guron, Gregor 1967-
Issue Date: 1998
University: Göteborgs universitet/University of Gothenburg
Institution: Department of Physiology
Avdelningen för fysiologi
Date of Defence: 1998-02-27
Publication type: Doctoral thesis
Keywords: Angiotensin converting enzyme; angiotensin converting enzyme inhibitor; angiotensin II; kidney development; renal physiology; urine concentration; renal medulla
Abstract: The renin-angiotensin system (RAS) is important in the regulation of extracellular fluid volume and systemic blood pressure. In a previous study we accidentally found that pharmacological blockade of the RAS in neonatal rats with immature kidneys produced persistent renal morphological abnormalities. This observation suggested that the RAS, in addition to exerting its traditional functions in the control of circulatory homeostasis, may play a role in normal renal development. The aims of the pre... more
URI: http://hdl.handle.net/2077/11278
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

 

 

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