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Regulation of the platelet-derived growth factor β-receptor
(2001)
Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. ...
The inflammatory and immunogenic properties of the receptor for advanced glycation end products and its ligand, high mobility group box chromosomal protein 1
(2005)
Rheumatoid arthritis (RA) is a chronic systemic inflammatory joint disease, the pathogenesis of which is complex, involving a wide range of molecules. High mobility group box chromosomal protein 1 (HMGB1) is a nuclear ...
The renin-angiotensin system in renal tubulogenesis. Experimental studies in the rat
(2004)
The kidney and the renin-angiotensin system (RAS) are vital regulators of blood pressure and salt-water balance. In order to appropriately regulate circulatory homeostasis, the kidney must undergo normal development, in ...
On the initial inflammatory response to variations in biomaterial surface chemistry
(2004)
Aims. The aim of the present thesis was, firstly, to develop in vivo and ex vivo models for analysis of peri-implant exudate and implant adherent cells and, secondly, to characterize the early inflammatory response to ...
Interactions between whole blood and TiO₂ surfaces with focus on adhesion and activation of PMN granulocytes
(2000)
Foreign materials come in contact with the human body more and more frequently. The surgical procedure of inserting an implant into the body will cause bleeding, evoke an inflammatory response and initiate a healing process, ...
The role of bacterial endotoxin in the immature brain
(2004)
Aim: Epidemiological evidence suggests that infections may increase the vulnerability of the immature brain to further insults. The aim of this thesis was to investigate the role of bacterial endotoxin (lipopolysaccharide, ...
Proteoglycans, group IIA phospholipase A2, and lipoproteins.Potential involvement in atherogenesis
(2000)
Atherosclerosis is a multifactorial complex disease characterized by a focal accumulation of ApoB-100 containing lipoproteins, extracellular matrix (ECM), and cells in the arterial intima accompanied by an inflammatory ...
Arthritogenecity of RNA and its degradation products
(2006)
Viral infections often lead to arthralgias and overt arthritic states. Expression of double stranded RNA (dsRNA) is a common feature of all viruses during their replication and it has been suggested that it is able to ...