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Modeling and exploring human IRE1 as a strategy to design novel inhibitors: a computational approach
(2019-12-12)
Inositol Requiring Enzyme 1 (IRE1) is a bifunctional
serine/threonine kinase and endoribonuclease that is the major mediator of
the Unfolded Protein Response (UPR) during endoplasmic reticulum (ER) stress.
The association ...