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A role of CD44 in atherosclerosis? Studies in mice and humans
(2009-01-12)
Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the ...
The effect of hypoxia on macrophage proteoglycans: potential role in atherosclerosis
(2009-11-13)
A critical step in the development of atherosclerotic lesions appears to be the retention of low density lipoproteins (LDL) in the arterial wall, mediated by negatively charged proteoglycans (PG). Retained LDL is susceptible ...
Cardiovascular and metabolic control in obese children and adolescents
(2008)
Childhood obesity is an emerging risk factor for disease and mortality worldwide. Thecardiovascular consequences and prevention thereof need to be further investigated. Exerciseand weight loss are well examined and effective ...
Cardiovascular and metabolic control in obese children and adolescents
(2008-05-23)
Childhood obesity is an emerging risk factor for disease and mortality worldwide. The cardiovascular consequences and prevention thereof need to be further investigated. Exercise and weight loss are well examined and ...
Ultrasound evaluation of atherosclerosis and other cardiovascular sources of cerebral embolism
(2008-01-18)
The search for embolic sources has high priority in patients presenting with suspected cerebral embolism. Non-invasive cardiovascular ultrasound is frequently used to reveal the presence of carotid stenosis and cardiac ...
Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome
(2005)
The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those ...
The complement system in stherosclerosis and arthritis
(2004)
The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, ...
Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice
(2004)
Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development ...
Imaging of coronary artery function and morphology in living mice - applications in atherosclerosis research
(2007-05-04)
Atherosclerosis in the coronary arteries is the major reason for myocardial infarction and cardiovascular death. In the clinic, several imaging systems make it possible to study coronary artery function and morphology ...
Retention of atherogenic lipoproteins in atherogenesis
(2004)
Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. ...