Browsing by Subject "zebrafish"
Now showing items 1-6 of 6
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Cell-based models for studying paediatric high-grade gliomas
(2019-05-06)Brain tumours are the largest group of solid tumours in children and accounts for most cancer-related deaths. Astrocytoma is the largest group, representing almost half of the brain tumours, where high-grade glioma is one ... -
Effects of mixtures of endocrine disrupting chemicals – Thyroid disruption and behavioural effects in fish models
(2022-01-07)Wildlife and humans are continuously exposed to thousands of man-made compounds, including chemicals that are able to act as endocrine disruptors (EDCs). These pollutants are able to affect vital processes including brain ... -
On oxytocin and social behavior
(2018-10-19)Complex social cognitive processes underlie social behavior. Oxytocin has long been recognized as crucial in social behavior in animals, but its role in regulating human social cognition and behavior is less clear, ... -
Physiological roles of amyloid precursor protein in vivo - zebrafish as a model
(2021-10-26)Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). APP ... -
The role of microglia in Alzheimer's disease - Investigating mechansims regulating amyloid-β clearance
(2016-05-31)Alzheimer’s disease (AD) is the most common form of dementia today. The disease is characterized by the presence of amyloid plaques and neurofibrillary tangles in the brain, accompanied by a progressive neurodegeneration ...