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Now showing items 31-40 of 40
Imaging Optodes
(2006)
Experimental studies of cluster ions containing water, ammonia, pyridine and bisulphate
(2011-10-06)
Molecular cluster ions are fascinating subjects of study. Bridging the size gap between molecules and bulk, they often display non-trivial size dependent behaviour and properties. As an example, for some cluster types there ...
Fluxes and transformation of carbon in the Siberian shelf seas under changing environment
(2012-05-16)
The Arctic is especially vulnerable to the increased air temperature caused by emissions of greenhouse gases to the atmosphere, carbon dioxide being one of them. In this thesis, both fieldwork and modelling of the East ...
Absolute Asymmetric Synthesis
(2011-04-18)
Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of ...
Chiral Lithium N,P-amide Complexes. Synthesis, Applications and Structural Studies by NMR and DFT.
(2011-11-28)
Enantiospecific synthesis reactions are of intense interest, owing to the increasing
request for enantiopure compounds in both research and industry. Lithium amides
containing a secondary chelating group are a class of ...
Experimental studies of ice particle formation with tropospheric relevance
(2008-11-07)
In their fourth assessment report, the Intergovernmental Panel on Climate Change points out the
influence of particles suspended in air, known as an aerosol, as the main uncertainty in the
understanding of the climate ...
Experimental and computational investigation of affinity and selectivity factors in CYP2D6 and CYP3A4 mediated metabolism
(2010-09-02)
The assessment of ADME properties and metabolic behavior of a drug is central in drug discovery and drug design. The main target for studies of metabolic properties is the Cytochrome P450 (CYP), which is responsible for ...
Limonene Hydroperoxides in Allergic Contact Dermatitis. Radical Formation, Sensitizing Capacity and Immunogenic Complex Formation.
(2009-04-24)
Contact allergy to fragrance compounds is an increasing problem in the western countries today. R-Limonene is one of the most common fragrance compounds; it is used in hygiene products and cosmetics as well as in industrial ...
Improving Drug Discovery Decision Making using Machine Learning and Graph Theory in QSAR Modeling
(2010-02-12)
During the last decade non-linear machine-learning methods have gained popularity among QSAR
modelers. The machine-learning algorithms generate highly accurate models at a cost of increased model
complexity where simple ...