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New insights in contact allergy and drug delivery. A study of formulation effects and hapten targets in skin using two-photon fluorescence microscopy
(2011-11-08)
The skin is a remarkable barrier, protecting us from invasion of e.g. harmful microorganisms and UV-radiation. However, the skin is not adopted to resist repeated exposure to the multitude of xenobiotics introduced into ...
Conformational Dynamics of Rhodopsins Visualized by Time-resolved Wide Angle X-ray Scattering
(2011-10-27)
Rhodopsins are a family of light-sensitive proteins found in the cellular membranes of a
wide range of living organisms. These membrane proteins share a common molecular
architecture and are able to use light energy ...
Homochiral Crystals for Selective Synthesis
(2011-04-13)
Six new coordination compounds were prepared from monodentate sulfide
ligands and copper(I) halides and their crystal structures were determined
by single-crystal X-ray diffraction. The aim was to prepare coordination
polymers ...
Algorithms for analysis of NMR projections: Design, implementation and applications
(2011-03-29)
With an increasing rate of protein expressions the need for fast protein characterization has become more important. Protein NMR has long been an important contributor for protein characterization; being one of a few ...
Regulation of electron donation to photosystem 1
(2011-05-09)
Photosynthesis is the process where energy from light is used to catalyze the formation of energy-rich molecules such as NADPH and ATP. These reactions are in fact the result of a long series of electron-transfer reactions ...
Influence of resuspension on sediment-water solute exchange and particle transport in marine environments
(2011-11-24)
Marine sediments contain a large pool of nutrients, which if released would contribute to increased eutrophication, in spite of decreased nutrient loads from land and atmosphere. Resuspension is a process, which might ...
MECHANISTIC INVESTIGATIONS OF TRANSITION METAL CATALYZED REACTIONS
(2011-12-14)
Transition metal catalyzed reactions have had a large impact on the human progress for the last century. Several extremely important areas, such as the agricultural industry and the plastic industry, have benefited from ...
Synthesis of Novel Inhibitors of IdeS, a Bacterial Cysteine Protease Including Studies of Stereoselective Reductive Aminations
(2011-09-30)
Abstract
The cysteine protease IdeS is an IgG degrading enzyme secreted by the bacterium Streptococcus
pyogenes to evade the human immune system. In this thesis several inhibitors of IdeS have been
synthesized and ...
AQUAPORINS: Production Optimization and Characterization
(2011-05-05)
Aquaporins are water facilitating proteins embedded in the cellular membranes. Such channels have been identified in almost every living organism – including humans. They are vital molecules and their malfunction can lead ...
Physical properties and processes of secondary organic aerosol and its constituents
(2011-10-27)
Atmospheric aerosol particles are involved in several important processes including the formation of clouds and precipitation. A considerable fraction of the ambient aerosol mass consists of organic compounds of both primary ...