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Lipoproteins in the postprandial state: Studies on the metabolism of triglyceride-rich lipoproteins using multicompartmental models


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Title: Lipoproteins in the postprandial state: Studies on the metabolism of triglyceride-rich lipoproteins using multicompartmental models
Authors: Björnson, Elias
E-mail: elias.bjornson@wlab.gu.se
elias.bjornson@gmail.com
Issue Date: 21-May-2021
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Medicine. Department of Molecular and Clinical Medicine
Parts of work: Björnson, E., Packard, C. J., Adiels, M., Andersson, L., Matikainen, N., Söderlund, S., ... & Borén, J. (2019). Investigation of human apoB48 metabolism using a new, integrated non‐steady‐state model of apoB48 and apoB100 kinetics. Journal of internal medicine, 285(5), 562-577
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Björnson, E., Packard, C. J., Adiels, M., Andersson, L., Matikainen, N., Söderlund, S., ... & Borén, J. (2020). Apolipoprotein B48 metabolism in chylomicrons and very low‐density lipoproteins and its role in triglyceride transport in normo‐and hypertriglyceridemic human subjects. Journal of internal medicine, 288(4), 422-438
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Taskinen, M. R., Björnson, E., Matikainen, N., Söderlund, S., Pietiläinen, K. H., Ainola, M., ... & Borén, J. (2021). Effects of liraglutide on the metabolism of triglyceride‐rich lipoproteins in type 2 diabetes. Diabetes, Obesity and Metabolism
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Taskinen, M. R., Björnson, E., Kahri, J., Söderlund, S., Matikainen, N., Porthan, K., ... & Borén, J. (2020). Effects of Evolocumab on the Postprandial Kinetics of Apo (Apolipoprotein) B100-and B48-Containing Lipoproteins in Subjects With Type 2 Diabetes. Arteriosclerosis, Thrombosis, and Vascular Biology, ATVBAHA-120
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Date of Defence: 2021-06-10
Disputation: Torsdagen den 10 juni 2021, klockan 13.00, Sahlgrens aula Blå stråket 5, Sahlgrenska universitetssjukhuset, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Lipoprotein metabolism
Atherosclerotic cardiovascular disease
Abstract: Lipoproteins are lipid-containing spherical particles that circulate in the human blood stream. The reason for their intense study over the decades is their ability to cause atherosclerosis1. Atherosclerotic cardiovascular disease (ASCVD) remains as the single largest cause of death worldwide; and here in Sweden, around a third of all deaths can be attributed to the category: diseases of the circulatory system2. The strength of evidence that low-density lipoproteins (LDL) cause ASCVD is very hig... more
ISBN: 978-91-8009-300-2 (PRINT)
978-91-8009-301-9 (PDF)
URI: http://hdl.handle.net/2077/68070
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för medicin

 

 

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