Masteruppsatser / Medicinsk strålningsvetenskap
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Optimization of Kidney Dosimetry: Determination of Recovery Coefficient for Kidneys and SPECT/CT Imaging of [177Lu]Lu-DOTATATE/TOC
(2025-10-06)Purpose: Peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTATATE/TOC is an effective treatment for neuroendocrine tumors, but this treatment also involves an unwanted radiation dose to the kidneys. Dosimetry ... -
Evaluation of Synthetic Ground Truth for Semantic Brain Image Segmentation - Developing a Database of Synthetic Images with Ground-Truth Segmentations for Practical Application Assessment
(2025-09-10)Introduction: Automated brain image segmentation plays an important role in large-scale neuroimaging research and shows growing potential for clinical applications. Traditional segmentation pipelines rely on manually ... -
Automatic exposure control for digital radiography without a physical anti-scatter grid
(2025-09-04)Purpose: This study aimed to find a factor R for different parameter settings that can be used to adjust the AEC preset value, in order to maintain a constant amount of primary radiation to the detector when the anti-scatter ... -
Characterization of spinal tissue in lumbar spinal stenosis by advanced image analysis of MR images
(2025-03-24)Background. Lumbar spinal stenosis (LSS) is known for causing back and leg pain due to nerve compression but the impact on structures such as intervertebral discs (IVDs), vertebrae, and ligaments is still poorly understood. ... -
Moving towards clinical implementation of a deep-learning brain tumour segmentation algorithm: DICOM server integration
(2025-03-05)Aim: This research project is part of a larger initiative where the aim is to develop a software tool that supports radiologists by providing more accurate tumour volume measurements on magnetic resonance imaging (MRI) ... -
Opportunistic screening for osteoporosis with CT performed before dose planning for radiation therapy
(2025-03-05)Purpose: Radiotherapy can negatively impact bone health, affecting the activity of osteoblasts, osteoclasts, and osteocytes, leading to dysfunction in bone remodeling and reduced bone mineral density (BMD). This increases ... -
Assessment of bioaccessibility of naturally occurring radionuclides from snus to consumers
(2025-03-05)Purpose: Naturally occuring radionuclides can be found in everything we consume, including the tobacco used to make snus. This study aimed to investigate the presence of naturally occurring radionuclides in snus, their ... -
Can cooking practices affect dietary exposure to 210Po in seafood?
(2024-11-13)Background: The estimated yearly worldwide average exposure to radiation is about three mSv, with 2.4 mSv coming from natural radiation sources. 210Po is a highly radiotoxic decay product of 238U and a major contributor ... -
Developing an Energy Resolution Model for Monte Carlo-Based SPECT Simulation and Reconstruction Using a GE Discovery NM/CT 670 Pro System
(2024-09-23)Aim: In order to apply Monte Carlo (MC)-based algorithms for simulations of gamma camera acquisitions, the intrinsic characteristics of the system must be properly defined. This study aimed to determine the energy resolution ... -
Treatment Plan Quality for Deep Inspiration Breath-Hold Breast Cancer Radiation Therapy - Comparison between Conventional Technique and Modulated Approaches
(2024-09-23)Introduction: Breast cancer remains a significant health concern globally, impacting millions of individuals each year [1]. Radiation therapy, an adjuvant to surgery and chemotherapy, aims to eliminate residual cancer ... -
Age-Related Late Effects in Rat Thyroids After Internal 131I Exposure
(2024-09-23)The Chernobyl nuclear accident left many questions in its wake. One of these questions was why children affected by the radioactive fallout seemed to have a higher incidence of thyroid cancer compared with adults in the ... -
VALUATION OF CHALLENGES IN SPECT-BASED DOSIMETRY IN THE TREATMENT OF METASTATIC PROSTATE CANCER WITH 177LU-PSMA-617
(2024-09-23)Introduction: In nuclear medicine, targeted radioligand therapy is an established treatment option for metastatic cancer disease. A radioactive isotope is attached to a carrier molecule that will specifically bind to a ... -
Investigating the Impact of Imaging Parameters on Quantification and Interpretation in Brain PET
(2024-06-19)Rationale CortexID software (GE Healthcare) assists in interpreting and assessing FDG and beta-amyloid brain Positron Emission Tomography (PET) images for neurological disorders. It provides Z-scores that indicate abnormal ... -
Compartment model for radon-induced absorbed dose in lungs
(2024-04-23)Inhalation of radon gas and radon daughters has since a long time been reported as the second leading cause of lung cancer after smoking. The biological hazards make it therefore important to quantify the absorbed doses ... -
Evaluating aperture shape controller (ASC) in modulated radiation treatments
(2023-09-28)To decrease aperture complexity, the aperture shape controller (ASC) is a recently introduced function in Eclipse external beam planning (Varian Medical Systems, Palo Alto, USA). ASC works within the photon optimizer, ... -
Anatomical segmentation of the human brain: comparative assessment of two automatic methods
(2023-08-22)Magnetic Resonance Imaging (MRI) is a robust and versatile imaging modality and an integral component of a lot of studies, especially when performing quantitative analysis. MRI is the preferred method of imaging the ... -
Apoptosis induction in breast cancer cells after radiotherapy and potential radiosensitizers
(2023-06-27)Background. Today breast cancer is the foremost cancer death type amongst women around the world. At present some of the toughest challenges in the clinic is recurrent, radioresistant breast cancer, and metastatic breast ... -
Preprocessing for intravoxel incoherent motion analysis in the brain - Signal drift correction
(2023-04-17)Diffusion magnetic resonance imaging (dMRI) is a diagnostic imaging technique that is sensitized to the movement of water molecules in tissues. Intravoxel incoherent motion (IVIM) analysis can be used to estimate blood ... -
Brain morphometry in Parkinson’s disease
(2023-03-02)Abstract Purpose The purpose of this brain morphometry study was to examine the volumes of different regions of the brain by research participants with Parkinson’s disease. Method To carry out the study, MR (magnetic ... -
Monte Carlo evaluation of static and dynamic 6FFF treatments - Evaluation of dose distributions calculated with AAA, Acuros XB, and Collapsed Cone (RayStation and DoseCheck)
(2023-02-23)There are several benefits to removing the standard flattening filter and using so-called flattening filter free (FFF) treatments in external radiation therapy with photons. The main advantage is the possibility of ...
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