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The cost-effectiveness of biological therapy cycles in the management of Crohn’s disease


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Title: The cost-effectiveness of biological therapy cycles in the management of Crohn’s disease
Authors: Bolin, Kristian
Hertervig, Erik
Louis, Edouard
Issue Date: Nov-2018
Extent: 32
Publication type: report
Publisher: University of Gothenburg
Organization: Dept. of Economics, University of Gothenburg
Series/Report no.: Working Papers in Economics
745
Keywords: infliximab
immunosuppressant
de-escalation
cost-effectiveness
Abstract: Objectives: to examine the cost-effectiveness of continued treatment for patients with moderate-severe Crohn’s disease in clinical remission, with a combination of anti-TNFα (infliximab) and immunosuppressant therapy compared to two different withdrawal strategies (1) withdrawal of the anti-TNFα therapy, and (2) withdrawal of the immunosuppressant therapy, respectively. Material and methods: A decision-tree model (Markov type) was constructed mimicking three treatment arms: (1) continued com... more
ISSN: 1403-2465
Description: IE
URI: http://hdl.handle.net/2077/58171
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