• The Epidemiology of Idiopathic Normal Pressure Hydrocephalus Prevalence, Incidence, and Radiological Features in 70-Year-Olds 

  Constantinescu, Clara (2025-10-27)

  Background: Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible but underdiagnosed condition in older adults. Population-based data on disease incidence and progression remain limited. This thesis ...

• Frailty and nutrition in the context of ageing: Exploring dietary habits among community-dwelling older adults 

  Johannesson, Julie (2025-10-15)

  As life expectancy increases, the ageing population faces a higher risk of illness and altered nutritional needs, making it essential to study factors that can help maintain or improve health. The overall aim of this thesis ...

• Biomarkers in Ischemic Stroke and Cerebral Small Vessel Disease 

  Holmegaard, Lukas (2025-10-15)

  The overall aim was to investigate whether biomarkers can improve the understanding and management of ischemic stroke and cerebral small vessel disease (SVD). The studies were based on the Sahlgrenska Academy Study on ...

• Cerebrospinal fluid studies of major psychiatric disorders 

  Göteson, Andreas (2025-10-10)

  Bipolar disorder and schizophrenia are clinically related, severe psychiatric disorders affecting 2–3% of the global population. With early onset, a life-long course, and limited treatment options, they cause major burden. ...

• Fluid biomarkers for frontotemporal lobar degeneration and related diseases — discovery and clinical validation 

  Joel, Simrén (2025-09-26)

  Frontotemporal dementia (FTD) spectrum disease encompasses a wide range of progressive clinical syndromes, including behavioral changes, progressive language deterioration, sometimes in combination with motor neuron ...

• Cerebrospinal Fluid - Composition and Dynamics Across Contexts 

  Lyckenvik, Tim (2025-09-18)

  Cerebrospinal fluid (CSF) offers a rare vantage point into the hidden chemistry of the brain. Its composition arises from a finely tuned balance of production, circulation, and interstitial exchange, regulated by ion ...

• White adipose tissue functionality - Biological sex- and PCOS-related differences 

  Perian, Charlène (2025-09-16)

  Adipose tissue is a dynamic energy storage and endocrine organ that plays a central role in metabolic regulation. Its function and distribution differ between the sexes, influencing the susceptibility to metabolic and ...

• The framing of Swedish forensic mental health services - Practical implications of ethical valuation, legally defined goals, and patients' needs 

  Pedersen, Sven Henrik (2025-09-10)

  Forensic mental health services (FMHS) face challenges due to a limited evidence base for common interventions and an unclear framing of their fundamental task in relation to the patients they serve. This creates difficulties ...

• Taking older persons seriously: Exploring personcentred and participatory approaches for fair responsibility in health and social care 

  Hermansen Østby, Roar (2025-09-04)

  Introduction and aim: As the older population grows, the need for care that respects their preferences becomes increasingly important. Frail and pre-frail persons, especially those in or approaching residential aged care ...

• Pathophysiological mechanisms and clinical value of novel blood-based tau biomarkers 

  Gonzalez Ortiz, Fernando (2025-08-27)

  The use of fluid biomarkers, which serve as biological signatures of physiological processes or disease states, has a great impact on the field of neurology when it comes to providing tools to better understand, diagnose, ...

• Female Offenders of Lethal and Severe Violence - Mental Health, Risk Factors for Criminality and Offence Behaviour 

  Trägårdh, Karin (2025-08-20)

  In about 10 % of homicides, offenders are females, forming an understudied group. The main aim of this thesis is to identify the qualities that distinguish female offenders of lethal and severe violence in terms of mental ...

• Addressing knowledge gaps in the brain ghrelin signalling system - its neural circuitry and role in foodlinked behaviours 

  Poelman, Renée (2025-08-18)

  The drive to seek out and consume food is a fundamental survival mechanism, orchestrated by the brain through a range of behaviours in response to both intrinsic signals of energy status and external food-related cues. ...

• The Neurobiological Pathway Towards Suicidal Ideation - Cerebrospinal Fluid Markers, Cognitive Impairment and Brain Imaging 

  Rymo, Irma (2025-07-03)

  In recent years, there has been increasing recognition of neurobiological factors as critical contributors to the vulnerability underlying suicidal behavior. This thesis examines the associations between synaptic ...

• Blood-based biomarkers in epilepsy 

  Akel, Sarah (2025-05-20)

  Blood-based biomarkers hold promise as minimally invasive and scalable tools to complement current diagnostic methods and potentially support clinical decision-making in epilepsy. This thesis explores blood biomarkers in ...

• Surface electromyography for improving upper limb function after stroke - Development of new rehabilitation tools 

  Muñoz Novoa, María José (2025-05-15)

  Background: Upper limb impairment is a major consequence after stroke, significantly affecting independence and quality of life. Various rehabilitation technologies have been developed to improve upper limb function, ...

• Adolescent-onset anorexia nervosa in the acute stage and after 30 years 

  Rydberg Dobrescu, Sandra (2025-04-29)

  Anorexia nervosa (AN) is a severe eating disorder (ED) that predominantly affects females in early adolescence. The overarching aim of this thesis has been to examine individuals with adolescent-onset AN in the acute stage, ...

• P-tau212: a novel biomarker for tau pathology in specific neurodegenerative diseases 

  Kac, Przemyslaw (2025-04-25)

  Tau protein is involved in multiple physiological processes in the central nervous system, one of which is microtubule stabilization. Post-translational modifications of tau, such as phosphorylation strictly regulate this ...

• Guillian-Barré syndrome: Epidemiology and biomarkers in blood and cerebrospinal fluid 

  Hafsteinsdóttir, Brynhildur (2025-04-15)

  Guillain-Barré syndrome (GBS) is a rare, potentially life-threatening disease. The incidence of GBS varies, and clusters can occur related to the increased prevalence of triggering events. Most patients recover well, but ...

• Functioning after COVID-19 – A long term follow-up of hospitalized patients using qualitative and quantitave methods 

  Larsson, Alexandra C (2025-04-09)

  ABSTRACT Background: In 2020, the novel SARS-CoV-2 virus triggered the COVID-19 pandemic, overwhelming healthcare systems worldwide and causing significant suffering. At the time, the long-term consequences of COVID-19 ...

• Sex-specific modulation of neurobehavioral outcomes - The intersection of sex steroids, gut peptides, and behavior 

  Börchers, Stina (2025-04-09)

  Despite ample evidence indicating that psychiatric disorders and their symptoms exhibit significant differences based on sex, research on their underlying mechanisms in females has historically been limited. This thesis ...

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