Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi: Recent submissions
Now showing items 21-40 of 479
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Executive functions and ERP Biomarkers in children and adolescents with ADHD and Autism
(2023-10-19)Executive Functions (EF) refers to skills that help us initiate, organize and evaluate activities. Problems with EF are associated with neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD) ... -
Hearing in advanced age Epidemiological, pathophysiological, and diagnostic perspectives from the Gothenburg H70 Birth Cohort Studies
(2023-10-16)The population aged 80 and above is expected to increase in the future resulting in an anticipated rise in health care demands. Age-related hearing loss (ARHL) is described as the third most common health condition ... -
Amyloid Maturation Patterns in Alzheimer's Disease - Novel chemical imaging of Aβ and Tau pathology
(2023-10-11)Alzheimer’s disease (AD) accounts for approximately 70% of dementia cases in Sweden. It can be of genetic origin i.e. familial form (fAD), sporadic form (sAD). AD is characterized by the deposition of amyloid and tau ... -
Upper extremity functioning in individuals with cervical or thoracic spinal cord injury - From body functions to participation
(2023-09-28)Background: A spinal cord injury (SCI) can lead to a range of impairments in various body functions, including the function of upper extremity, with severity varying from mild to severe. Long-term consequences for functioning ... -
Suicidality and depression in older adults: Prevalence, predictors, and outcomes
(2023-09-08)Older adults have the highest risk of suicide of all age groups. Depression is a major risk factor for suicide in late life, but is also associated with lower quality of life, somatic disorders, and premature death. The ... -
Gambling, alcohol and gender: Subjective effects and clinical characteristics
(2023-09-01)Gambling and alcohol are two recreational activities enjoyed by many people all over the world. Most with the purpose of leisure and social interaction with little or no consequence to impact daily life. For some however ... -
The relationship between cognition and ESSENCE in childhood
(2023-08-29)Aims: To examine the relationship between cognition and ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) features in children, ages 7-8 years. To investigate the importance of ... -
Pre/Peri/Earl-Life Exposures and Early Child Neurodevelopment: Results from the Japan Environment and Children's Study (JECS)
(2023-08-18)Background: Combinations of genetic and environmental factors contribute to aetiologies of neuropsychiatric problems and neurodevelopmental disorders (NDDs) in intricate manners. Among the environmental factors, exposures ... -
Oropharyngeal dysphagia in adults: Prevalence, professional practices, patient perspectives and treatment outcomes
(2023-05-25)Background: Oropharyngeal dysphagia (OD) is defined as any disruption in the transportation of food/liquids safely and efficiently from the mouth, through the pharynx and into the esophagus. The underlying causes of OD ... -
Machine learning and big data for personalized epilepsy treatment
(2023-05-23)Finding an effective anti-seizure medication (ASM) with minimal side effects is a challenge. Patient characteristics are used to guide treatment selection, but about half of the patients with epilepsy do not achieve seizure ... -
Cardiometabolic risk indicators in bipolar disorders
(2023-05-15)In addition to disabling mood episodes, bipolar disorders (BDs) predispose individuals to high cardiovascular disease (CVD) risk. This thesis explores the association between BDs and the metabolic risk indicators body mass ... -
Quality of drug treatment in older people from a medical primary care perspective and according to indicators
(2023-05-09)Background: Drug treatment in older people is particularly complex; the burden of disease increases by age, and patients in this age group are more sensitive to drug effects. As a knowledge resource for clinicians as well ... -
Seizure and non-seizure outcomes after epilepsy surgery in selected patient groups
(2023-05-09)This thesis addresses some understudied aspects of epilepsy surgery with special emphasis on children and adolescents. The specific aims were to analyse educational and employment outcomes after epilepsy surgery in ... -
lmproving diagnosis of central nervous system tumours using genetic and epigenetic tools
(2023-05-09)Brain tumor diagnostics has traditionally been based on histopathology stains. The introduction of immunohistochemistry stains resulted in improved ability to classify these often devastating tumors. The understanding of ... -
DIGIROP prediction models for severe retinopathy of prematurity
(2023-05-04)BACKGROUND: Retinopathy of prematurity (ROP), a preventable, potentially blinding eye disease, is primarily diagnosed in extremely preterm infants. Gestational age (GA) and birth weight (BW) are the most prominent risk ... -
The role of beta 3 adrenergic receptor in white adipocyte adiponectin exocytosis
(2023-05-03)In this thesis we define the physiological and underlying mechanisms involved in the white adipocyte adiponectin exocytosis, with a special focus on the beta 3 adrenergic receptor (β3AR) in health and metabolic disease. ... -
Electrically evoked compound action potentials as a tool for programming cochlear implants in children
(2023-05-03)Cochlear implants are generally the best treatment for young children with a profound hearing loss (or worse) when ordinary hearing aids cannot provide enough auditory stimulation. For these youngest recipients, there must ... -
Alcohol use among older adults: Population perspectives on prevalence, correlates, and consequences of drinking in Swedish 70-year-olds
(2023-04-25)Background: Alcohol consumption is a major contributor to global morbidity and mortality, as well as accidents and intentional injuries. Older adults may be particularly susceptible to these negative consequences due to ... -
Neural circuit mapping af orexigenic systems
(2023-04-21)Orexigenic systems in the brain process appetite and/or hunger information and ultimately coordinate feeding responses. These brain circuits are critical for survival and originally evolved to ensure that we consume ... -
Herpes virus retinitis - clinical and virological characteristics
(2023-04-19)In this thesis, we first aimed to determine whether there may be herpes virus deoxyribonucleic acid (DNA) in the aqueous humour of asymptomatic individuals (paper II). Presence of herpes simplex virus (HSV), varicella ...