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Now showing items 21-30 of 477
On detection, treatment and prevention of complications in paediatric cataract surgery
(2019-11-06)
Purpose: To find and validate methods for diagnosis, treatment and prevention of complications in paediatric cataract surgery.
Background: Cataract and glaucoma are major treatable blinding conditions in children. Surgery ...
Cognitive dysfunction studied in animal models of schizophrenia
(2006-12-01)
Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ...
From mice to men - astrocytes and neural progenitor cells in neural plasticity and regeneration
(2017-02-06)
Astrocytes, a key homeostatic cell type in the mammalian central nervous system (CNS), have various functions in health and diseases. In neurotrauma, stroke, epilepsy or neurodegenerative diseases, astrocytes become reactive, ...
Genetic studies of autism and autistic-like traits
(2015-01-09)
Autism spectrum disorder (ASD) is characterized by impairment in social interaction,
language impairment and repetitive behavior with varying degrees of severity. ASD
represents the lower end on a continuously distributed ...
Alzheimer’s Disease: effect of Tau-related genes on the pathology, neurochemistry and risk of disease
(2007-11-07)
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. The predominant sporadic form of AD is a genetically complex disorder probably involving a combination of genetic factors together with environmental ...
The role of the complement system in ischemic stroke and neural plasticity
(2013-10-29)
Evidence from experimental animal studies suggests that complement activation in the brain is a “double-edged sword” as it exerts beneficial or detrimental effects depending on the context. Here, we assessed whether ...
Parkinson's disease and motor function - a validation of the PLM method
(2013-09-27)
Aim: To validate the Posturo-Locomotor-Manual (PLM) test, an objective movement measurement system designed to measure movement disability in patients with Parkinsonism.
Method: The reliability of the PLM test was determined ...
Att vara agent i sitt eget liv - Hur självbestämmande kan förstås, uppfattas och utvärderas i en kontext av sköra äldre personer
(2014-02-21)
Syfte
Det övergripande syftet med avhandlingen var att definiera och beskriva självbestämmande i relation till sköra äldre personer, instrumentutvärdering för att skatta äldre personers självbestämmande samt utvärdera ...
Human iPSC-derived neuronal networks. Development and application for compound evaluation
(2022-02-03)
Research on human brain development and function in health and disease has been hampered by limited access to primary human tissue and limited translatability of animal studies. This knowledge gap is encouraging the use ...
Colonic barrier function in ulcerative colitis - Interactions between ion and mucus secretion
(2012-05-07)
Anion and mucus secretions have traditionally been looked upon as two separate parts of the epithelial defense system. The importance of anion secretion has been attributed to its role in creating the driving force for ...