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Now showing items 21-30 of 253
Colonic barrier function in ulcerative colitis - Interactions between ion and mucus secretion
(2012-05-07)
Anion and mucus secretions have traditionally been looked upon as two separate parts of the epithelial defense system. The importance of anion secretion has been attributed to its role in creating the driving force for ...
It´s never too late
(2014-04-15)
The overall aim of this thesis was to evaluate the effects of health-promoting and disease-preventive interventions on health and frailty in very old community-dwelling persons, and to explore the participants’ experiences ...
Mass spectrometric quantification of amyloid-beta in cerebrospinal fluid and plasma
(2015-10-07)
Alzheimer’s disease (AD) is the most common neurodegenerative disease among the elderly and accounts for 60-80% of all cases of dementia. Currently, the diagnosis of AD is based on cognitive tests and mental state exams, ...
Inflammation in the immature brain: The role of Toll like receptors
(2011-10-28)
Infection/inflammation and/or hypoxia-ischemia (HI) are major causes of perinatal brain injury. Toll-like receptors (TLRs), important components of innate immunity, have been shown to be involved in brain injury, both after ...
Psychological stress in relation to dementia and brain structural changes
(2012-09-03)
Psychological stress has been recognized as an increasing public health problem with serious consequences in both physical and mental health. Women reported a higher prevalence of psychological stress, especially in midlife. ...
Autism spectrum disorders - first indicators and school age outcome
(2016-02-10)
Background: Studies of early indicators, diagnostic stability and outcome at mid-school age in
children referred early in life for a suspected autism spectrum disorder (asd) have been few.
Aims: To examine early indicators ...
Re-evaluation of the hypothesis that LTP has two temporal phases and that the late phase is protein synthesis-dependent
(2015-02-19)
Long-term potentiation (LTP) is an activity-dependent increase in synaptic efficacy that is most studied in the hippocampus and that is considered a cellular substrate for learning and memory. Accepting the belief that the ...
The dynamic nature of participation - Experiences, strategies and conditions for occupations in daily life amongst persons with late effects of polio
(2016-02-26)
Aim: The overall aim of this thesis was to explore the conditions for daily occupations, and how these are reflected in the daily lives of people with the late effects of polio. Four studies (studies I–IV) are included in ...
In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions
(2019-05-23)
The adult brain has an inherently low capacity for tissue regeneration, and neurons lost to disease or injuries are normally not replaced. This becomes especially apparent when stroke or brain trauma occurs. The discovery ...
On Complications to Cataract Surgery
(2015-04-08)
Cataract surgery, meaning exchange of the opaque lens in the eye with an artificial lens, is nowadays one of the most successful surgical procedures ever known. It is also the most frequent surgery performed in the Western ...