Search
Now showing items 1-10 of 153
Predictors of severe kidney disease in long-term lithium treatment
(2024-04-22)
The thesis aims to advance the understanding of severe chronic kidney disease in lithium-treated patients through four observational studies in which subjects were recruited from the Sahlgrenska University Hospital laboratory ...
lnduction Therapies in Multiple Sclerosis - Clinical and immunological follow-up
(2024-03-21)
Multiple sclerosis (MS) is a chronic disease that damages the central nervous system. Its pathophysiology is complex, and consists of inflammation and degeneration from the disease onset. The treatment of MS has continuously ...
Regulation of amyloid beta generation and its involvement in synaptic function: studies in human iPSC-derived cortical neurons
(2024-02-21)
Alzheimer’s disease (AD) is a neurodegenerative disease that affects millions of individuals worldwide and exerts a profound societal and economic impact. Clinically characterized by a gradual loss of memory, cognitive and ...
A treatment seeking population with Gambling Disorder - Internet treatment, severity and gender
(2024-02-21)
Gambling is a common pastime all over the world, but can become harmful in excess and can even develop into an addictive behavior, a Gambling Disorder (GD). The aim of this thesis was to contribute to the clinical understanding ...
Children who screen positive for language delay but not autism: from 2.5 to 6 years of age
(2023-12-05)
Background: Language disorders (LDs) are prevalent, affecting approximately 10% of children. Among them, 7.5% have developmental language disorder (DLD), while 2.5% have LD associated with a known medical condition. In ...
Young Children with Autism in a Multiethnic Immigrant Population. Prevalence, Feeding Disorders, Early Detection, and Intervention
(2023-11-14)
Background: Autism is a neurodevelopmental condition characterized by a pattern of major
impairments in social communication and behavioural/sensory problems, with high rates of coexisting
neurodevelopmental and medical ...
Amyloid Maturation Patterns in Alzheimer's Disease - Novel chemical imaging of Aβ and Tau pathology
(2023-10-11)
Alzheimer’s disease (AD) accounts for approximately 70% of dementia cases in Sweden. It can be of genetic origin i.e. familial form (fAD), sporadic form (sAD). AD is characterized by the deposition of amyloid and tau ...
Suicidality and depression in older adults: Prevalence, predictors, and outcomes
(2023-09-08)
Older adults have the highest risk of suicide of all age groups. Depression is a major risk factor for suicide in late life, but is also associated with lower quality of life, somatic disorders, and premature death. The ...
Gambling, alcohol and gender: Subjective effects and clinical characteristics
(2023-09-01)
Gambling and alcohol are two recreational activities enjoyed by many people all over the world. Most with the purpose of leisure and social interaction with little or no consequence to impact daily life. For some however ...
The relationship between cognition and ESSENCE in childhood
(2023-08-29)
Aims: To examine the relationship between cognition and ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) features in children, ages 7-8 years. To investigate the importance of ...