In addition to disabling mood episodes, bipolar disorders (BDs) predispose individuals to high cardiovascular disease (CVD) risk. This thesis explores the association between BDs and the metabolic risk indicators body mass ...

Astrocytes, a key homeostatic cell type in the mammalian central nervous system (CNS), have various functions in health and diseases. In neurotrauma, stroke, epilepsy or neurodegenerative diseases, astrocytes become reactive, ...

Epilepsy surgery is a potentially curing treatment for a selected group of patients with drug-resistant focal epilepsy. Cognitive side-effects after temporal lobe resections (TLR) are well documented but it is still difficult ...

The present work summarizes investigations of the temporal correlates of brain activity elicited by gentle, moving touch on the hairy skin in healthy participants and in epilepsy patients. Light touch to the hairy skin ...

AUTISM SYNDROMES IN THREE BEHAVIOURAL PHENOTYPE CONDITIONS A clinical psychiatric study of 76 individuals with Möbius sequence, CHARGE syndrome, and oculoauriculovertebral spectrum Maria Johansson Institute of ...

Dementia is a clinical syndrome characterised by deterioration in cognitive functions, which causes personal suffering and societal challenges. Studies investigating the incidence, prevalence, and mortality of dementia are ...

Anxiety is a broad concept, difficult to detect and recognize. Expression may shift over the lifetime further complicating identification. Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders in ...

Perinatal brain injury is an important cause of mortality and morbidity and is associated with neurological disabilities such as those seen in cerebral palsy. Prematurity, especially in combination with very low birth ...

Cataract is an opacification of the eye lens, constituting the major cause of blindness globally. Oxidative stress is a key factor in the formation of cataract and female gender is a known risk factor for age-related ...

Tau is a protein predominantly expressed in neurons in the central nervous system (CNS), where it binds microtubules (MT), playing a major role regulating their dynamics and architecture. Under pathological conditions, tau ...