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The role of the complement system in ischemic stroke and neural plasticity
(2013-10-29)
Evidence from experimental animal studies suggests that complement activation in the brain is a “double-edged sword” as it exerts beneficial or detrimental effects depending on the context. Here, we assessed whether ...
Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms
(2006-11-08)
Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric ...
Plasticity of the developing glutamate synapse in the hippocampus
(2007-08-21)
Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. long-term potentiation - LTP) in response to specific patterns of activity. In the developing ...
Labile glutamate synaptic transmission onto CA1 hippocampal pyramidal neurons: regional, functional and developmental diversity
(2024-02-14)
A single neuron in the brain receives tens of thousands of glutamate synapses from other neurons, and these synapses can differ in their properties depending on their role in the neural circuit, during brain development ...