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Risk factors for dementia. Lifestyle, hormones, neurochemistry, and genetics
(2021-05-12)
Objective: The aim of this thesis was to expand the understanding about the effects of lifestyle factors, indicators of endogenous estrogens, and genetic factors on the risk of dementia and cerebrospinal fluid (CSF) markers ...
Biochemical markers in dementia - Exploring Swedish registry data and the human proteome
(2019-09-04)
Cerebrospinal fluid (CSF) biomarkers of neurodegenerative diseases have a wide scope of applications in diagnostics, prognosis assessment, disease staging, treatment evaluation and more. In this PhD project we aimed to ...
Deriving biomarkers from computed tomography using deep learning
(2022-09-23)
X-ray computed tomography (CT) and magnetic resonance imaging (MRI) are widely used structural neuroimaging modalities. For brain atrophy assessment and volumetric quantification using automated methods, MRI is the preferred ...