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GLIAL HEMICHANNELS: A NEW ROUTE FOR CHEMICAL COMMUNICATION IN BRAIN
(2008-03-25)
The extracellular neurochemistry determines normal brain function and the faith of neurons after insults such as stroke. This thesis concerns the effect of extracellular events related to intense neuronal stimulation and ...
Astrocyte metabolism following focal cerebral ischemia
(2006-11-16)
Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of
an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel.
Despite ...
Astrocyte-mediated short-term synaptic depression
(2009-09-09)
Short-term synaptic plasticity, the activity-dependent regulation of synaptic efficacy that occurs in the timeframe of milliseconds to seconds, is a fundamental property of the synapse, mostly attributed to changes in ...
Plasticity of the developing glutamate synapse in the hippocampus
(2007-08-21)
Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. long-term potentiation - LTP) in response to specific patterns of activity. In the developing ...