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Cognitive dysfunction studied in animal models of schizophrenia
(2006-12-01)
Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ...
Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms
(2006-11-08)
Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric ...
Astrocyte metabolism following focal cerebral ischemia
(2006-11-16)
Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of
an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel.
Despite ...
Late Neuropsychiatric Consequences of Stroke in the Elderly
(2006-11-07)
Cognitive impairments and depression have considerable impacts on rehabilitation, quality of life and mortality after stroke. The understanding of cognitive and mood impairments in old and, in particular, very old stroke ...
The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma
(2006-11-28)
Astrocytes are the most abundant cell type in the central nervous system (CNS) and
increasing evidence now suggests that they play an active role in various brain functions.
Astrocytes are involved in the induction and ...
Whiplash-associated disorders from a physical therapy and health-economic perspective. A study of an active physical therapy involvement and intervention for the treatment of acute whiplash-associated disorders and an analysis of its costs and consequences.
(2006-05-31)
Whiplash-associated disorders (WAD) resulting from a biomechanical
event in motor vehicle collisions is a major cause of suffering and high
costs to society. The overall aim of this thesis was to evaluate the ...
N-acetylaspartate in brain - studies on efflux and function
(2006-10-16)
N-acetylaspartate (NAA) is an amino acid derivative present in high concentration in the brain. The function of NAA is still unsettled in spite of 50 years of research. The mainly neuronal synthesis and glial breakdown of ...
Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells
(2006-11-28)
The most common fate of developing ovarian follicles is demise due to a process known as atresia. Regulation of atresia is dependent on the developmental stage of the follicles, resulting in a continuous reduction of the ...
Conditional and non-conditional reward-related responses to alcohol - nicotinic mechanisms
(2006-11-14)
The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine ...