Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ...

Alzheimer’s disease (AD) is the most common type of dementia. The cause of the disease is unknown, but a substantial amount of evidence suggest that the disease is started by an imbalance in the production and clearance ...

Mild cognitive impairment (MCI) is a diagnosis frequently used in dementia research and in memory clinics. MCI is meant to identify patients without dementia, but with cognitive decline beyond what is considered normal, ...

Cognitive deficits are the single strongest predictor of functional outcome in patients with schizophrenia. Furthermore, these deficits are not satisfactorily alleviated by available antipsychotic treatment. Functional ...

The prefrontal cortex has been extensively linked to several cognitive domains that are severely compromised in schizophrenia. It has therefore become a key region for studies on the disabling cognitive dysfunction commonly ...

Radiotherapy is used in the treatment of pediatric brain tumors and is often associated with debilitating late effects, such as intellectual impairment. Areas in the brain harboring stem cells are particularly sensitive ...

Even though the hallmark of bipolar disorder is recurrent episodes of elevated or depressed mood, mounting evidence suggests that cognitive impairment is a prominent characteristic of bipolar disorder. The heterogeneity ...

Screening of cognitive functions Evaluation of methods and their applicability in neurological rehabilitation Caisa Hofgren, Institute of Neuroscience and Physiology/Rehabilitation Medicine, The Sahlgrenska Academy at the ...

Abstract Aim: The aim of this thesis was to explore the life situation one year after an apparently mild stroke, and to compare life satisfaction between patients and their spouses. Method: Seventy-five patients with ...

The concept of reserve stems from the observation that premorbid factors, e.g. education, result in variation in the response to any kind of brain pathology. As subjects with higher reserve tolerate more neuropathology, ...