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Febrile Seizures and associated neurodevelopmental disorder
(2020-01-22)
Background: Febrile seizures (FS) are common in young children. There is a lack of knowledge about possible associations between FS and the child’s cognitive and behavioural development. Aim: Gain further insight into the ...
Physical activity on prescription in primary care. Impact on physical activity level, metabolic health and health-related quality of life, and its cost-effectiveness - a short- and long-term perspective
(2020-10-08)
Non-communicable diseases (NCDs) are the leading cause of death globally
and one of the major health challenges of the 21st century. In Sweden, NCDs
are estimated to account for 90 % of all deaths. Strong evidence indicates ...
Human iPSC-derived neuronal networks. Development and application for compound evaluation
(2022-02-03)
Research on human brain development and function in health and disease has been hampered by limited access to primary human tissue and limited translatability of animal studies. This knowledge gap is encouraging the use ...
The role of glycoproteins in glomerular pathophysiology
(2021-09-01)
Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no ...
Treatments and outcomes in bipolar disorder
(2020-11-02)
Bipolar disorder is defined by recurring mood episodes and patients
have a markedly increased risk of suicide. Pharmacological and psychological
treatments for bipolar disorder have proven efficacy in clinical
trials ...
Internationally adopted children with unilateral cleft lip and palate - longitudinal perspectives on speech production and language ability
(2020-05-13)
Many children with cleft lip and palate have been adopted to Sweden. Most had had no palatal closure performed in their native countries and received their first palatal surgery in Sweden while acquiring a new first language. ...
Paracrine control of glucagon secretion in the pancreatic α-cell: Studies involving optogenetic cell activation
(2020-06-12)
ABSTRACT
The mechanisms controlling glucagon secretion by α-cells in islets of Langerhans
were studied. We generated mice with the light-activated ion channel ChR2
specifically expressed in β-, α-, and δ-cells, and ...
Natural course and long-term prognosis in idiopathic Normal Pressure Hydrocephalus - the effect of delayed surgery and clinical factors on outcome and survival
(2020-05-07)
Idiopathic Normal Pressure Hydrocephalus, iNPH, causes gait and balance difficulties, urinary incontinence and cognitive decline in mainly older persons and is treatable by insertion of a cerebrospinal fluid diverting ...
Physical fitness and exercise in adults with congenital heart disease
(2020-04-14)
Background: The population of patients with adult congenital heart disease (ACHD) is growing, and the estimated life expectancy has increased. Therefore, factors related to lifestyle, such as physical activity (PA), exercise, ...
On Cyclodeviation - Strategies for Investigation, Management and quality of Life
(2020-06-04)
Introduction: Cyclodeviation is a form of strabismus that is not externally visible. It is measured subjectively and in degrees, as incyclotorsion or excyclotorsion. The perception of subjective tilting does not always ...