Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
Now showing items 387-406 of 479
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Reward-related genes and alcohol dependence
(2010-04-13)Introduction: The rewarding properties of alcohol are mediated by the brain reward systems, specifically by the cholinergic-dopaminergic reward link, involving both nicotinic acetylcholine receptors (nAChRs) as well as the ... -
Risk factors for dementia. Lifestyle, hormones, neurochemistry, and genetics
(2021-05-12)Objective: The aim of this thesis was to expand the understanding about the effects of lifestyle factors, indicators of endogenous estrogens, and genetic factors on the risk of dementia and cerebrospinal fluid (CSF) markers ... -
The role of beta 3 adrenergic receptor in white adipocyte adiponectin exocytosis
(2023-05-03)In this thesis we define the physiological and underlying mechanisms involved in the white adipocyte adiponectin exocytosis, with a special focus on the beta 3 adrenergic receptor (β3AR) in health and metabolic disease. ... -
The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta
(2008-11-14)Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there ... -
The role of progesterone in the regulation of ciliary activity in the fallopian tube
(2009-11-13)The overall aim of this thesis was to investigate the distribution and regulation of membrane progesterone receptors (mPRs) that may be involved in regulating ciliary activity in the fallopian tube. The fallopian tube ... -
The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma
(2006-11-28)Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and ... -
Screening and diagnosis of autism spectrum disorders
(2012-04-04)Objectives: Develop and examine a new screening and diagnostic framework for autism spectrum disorders (ASD), and study the prevalence of ASD in 2-year-old children in Gothenburg. Methods: Psychometric properties of the ... -
Screening of cognitive functions. Evaluation of methods and their applicability in neurological rehabilitation.
(2009-05-15)Screening of cognitive functions Evaluation of methods and their applicability in neurological rehabilitation Caisa Hofgren, Institute of Neuroscience and Physiology/Rehabilitation Medicine, The Sahlgrenska Academy at the ... -
Se och hör mig. Personer med förvärvad dövblindhets erfarenheter av delaktighet, rehabilitering och medborgerligt liv
(2016-12-20)Introduction and objective: There are very few research studies about the experiences of living with deaf blindness. The objective of this dissertation is to capture the experiences of people with acquired deafblindness ... -
Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands
(2009-09-17)Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in ... -
Seizure and non-seizure outcomes after epilepsy surgery in selected patient groups
(2023-05-09)This thesis addresses some understudied aspects of epilepsy surgery with special emphasis on children and adolescents. The specific aims were to analyse educational and employment outcomes after epilepsy surgery in ... -
Self-reported activity and participation in persons with haemophilia living in Sweden
(2016-08-30)Background: Haemophilia is a hereditary disease caused by deficiency of clotting factor VIII or IX. Recurrent joint bleeding episodes can lead to haemophilia arthropathy, a condition affecting daily activities and participation ... -
Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome
(2007-06-18)Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although ... -
Serotonin in Fear and Anxiety
(2020-10-16)That the neurotransmitter serotonin (5-HT) has a central role in fear and anxiety is supported by numerous experimental and clinical studies. Arguably the most illustrative example is the effect of serotonergic-acting ... -
Sex differences in behavior and metabolism
(2023-11-16)Men and women exhibit distinct illness patterns and disparate responses to pharmacotherapies. However, there is a scarcity of preclinical studies that systematically compare the sexes. The overarching aim of this thesis ... -
Sex steroids and social behavior: from mouse to human
(2016-04-11)Social behavior is a classification of various behaviors such as sexual behavior, aggressive behavior, social memory and sociability. These behaviors are under the regulation of the brain, and the sex steroids influence ... -
Shedding light on cognitive control
(2020-05-18)This thesis aimed to investigate the ability to adjust cognitive processes and behavior, i.e., cognitive control, and its related functional activity in the cortex. The optical imaging technique functional near-infrared ... -
Short- and long-term neuronal plasticity in hippocampal CA1 region of rat
(2010-06-14)The brain is highly plastic, displaying both short- and long-term changes, resulting from developmental processes as well as learning and memory. Moreover, short-term plasticity such as paired pulse facilitation and ... -
Signal identification for visual electrophysiological recordings. A comparison of signal analysis techniques and their application to clinical electrophysiology of vision.
(2012-05-24)Aims: The aim of this thesis was to investigate the use of objective methods for the analysis of visual electrophysiological recordings. Specifically can signal identification algorithms identify electrophysiological signals ... -
Sleep, sense of coherence and suicidality in suicide attempters
(2009-01-26)A suicide attempt is a strong predictor of future suicide. The management of patients who self-harm presents a challenge for psychiatric services. It is therefore important to identify factors that may be related to ...