Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
Now showing items 380-399 of 477
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The relationship between cognition and ESSENCE in childhood
(2023-08-29)Aims: To examine the relationship between cognition and ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) features in children, ages 7-8 years. To investigate the importance of ... -
The reserve concept in patients with Mild Cognitive Impairment - new approaches
(2010-03-26)The concept of reserve stems from the observation that premorbid factors, e.g. education, result in variation in the response to any kind of brain pathology. As subjects with higher reserve tolerate more neuropathology, ... -
Respiratory burst and severity of demyelinating diseases
(2010-09-23)Multiple sclerosis (MS) and the Guillain-Barré syndrome (GBS) are tissue-specific inflammatory diseases of the central and the peripheral nervous system, respectively. A contemporary analysis infers that these are complex ... -
Restrictive eating disorders: aetiological, epidemiological and neurodevelopmental aspects
(2020-11-20)Restrictive Eating Disorders (EDs), including Avoidant/Restrictive Food Intake Disorder (ARFID) and Anorexia Nervosa (AN), are characterised by severely restricted food intake, commonly leading to substantial weight loss ... -
Revealing the complex nature of amyloid beta and its relation to dementia
(2020-10-20)Alzheimer disease (AD) is the most common type of dementia and characterized by the accumulation of amyloid plaques in the extracellular space of the brain parenchyma. Amyloid plaques consist of amyloid beta peptides (Aβ). ... -
Reward-related genes and alcohol dependence
(2010-04-13)Introduction: The rewarding properties of alcohol are mediated by the brain reward systems, specifically by the cholinergic-dopaminergic reward link, involving both nicotinic acetylcholine receptors (nAChRs) as well as the ... -
Risk factors for dementia. Lifestyle, hormones, neurochemistry, and genetics
(2021-05-12)Objective: The aim of this thesis was to expand the understanding about the effects of lifestyle factors, indicators of endogenous estrogens, and genetic factors on the risk of dementia and cerebrospinal fluid (CSF) markers ... -
The role of beta 3 adrenergic receptor in white adipocyte adiponectin exocytosis
(2023-05-03)In this thesis we define the physiological and underlying mechanisms involved in the white adipocyte adiponectin exocytosis, with a special focus on the beta 3 adrenergic receptor (β3AR) in health and metabolic disease. ... -
The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta
(2008-11-14)Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there ... -
The role of progesterone in the regulation of ciliary activity in the fallopian tube
(2009-11-13)The overall aim of this thesis was to investigate the distribution and regulation of membrane progesterone receptors (mPRs) that may be involved in regulating ciliary activity in the fallopian tube. The fallopian tube ... -
The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma
(2006-11-28)Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and ... -
Screening and diagnosis of autism spectrum disorders
(2012-04-04)Objectives: Develop and examine a new screening and diagnostic framework for autism spectrum disorders (ASD), and study the prevalence of ASD in 2-year-old children in Gothenburg. Methods: Psychometric properties of the ... -
Screening of cognitive functions. Evaluation of methods and their applicability in neurological rehabilitation.
(2009-05-15)Screening of cognitive functions Evaluation of methods and their applicability in neurological rehabilitation Caisa Hofgren, Institute of Neuroscience and Physiology/Rehabilitation Medicine, The Sahlgrenska Academy at the ... -
Se och hör mig. Personer med förvärvad dövblindhets erfarenheter av delaktighet, rehabilitering och medborgerligt liv
(2016-12-20)Introduction and objective: There are very few research studies about the experiences of living with deaf blindness. The objective of this dissertation is to capture the experiences of people with acquired deafblindness ... -
Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands
(2009-09-17)Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in ... -
Seizure and non-seizure outcomes after epilepsy surgery in selected patient groups
(2023-05-09)This thesis addresses some understudied aspects of epilepsy surgery with special emphasis on children and adolescents. The specific aims were to analyse educational and employment outcomes after epilepsy surgery in ... -
Self-reported activity and participation in persons with haemophilia living in Sweden
(2016-08-30)Background: Haemophilia is a hereditary disease caused by deficiency of clotting factor VIII or IX. Recurrent joint bleeding episodes can lead to haemophilia arthropathy, a condition affecting daily activities and participation ... -
Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome
(2007-06-18)Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although ... -
Serotonin in Fear and Anxiety
(2020-10-16)That the neurotransmitter serotonin (5-HT) has a central role in fear and anxiety is supported by numerous experimental and clinical studies. Arguably the most illustrative example is the effect of serotonergic-acting ... -
Sex differences in behavior and metabolism
(2023-11-16)Men and women exhibit distinct illness patterns and disparate responses to pharmacotherapies. However, there is a scarcity of preclinical studies that systematically compare the sexes. The overarching aim of this thesis ...